Distinct Changes of BTLA and HVEM Expressions in Circulating CD4+ and CD8+ T Cells in Hepatocellular Carcinoma Patients

Distinct Changes of BTLA and HVEM Expressions in Circulating CD4+ and CD8+ T Cells in Hepatocellular Carcinoma Patients

BTLA/HVEM (B and T lymphocyte attenuator/herpes virus entry mediator) pathways play a critical role in T cell suppression in tumor. However, its dynamic changes in different T cell subsets in peripheral blood and their clinical significance are largely unclear in cancer patients. In the current stud...

Full description

Saved in:

Bibliographic Details
Main Authors:	Jiayu Liu, Jiaqian Li, Min He, Geng-Lin Zhang, Qiyi Zhao
Format:	Article
Language:	English
Published:	Wiley 2018-01-01
Series:	Journal of Immunology Research
Online Access:	http://dx.doi.org/10.1155/2018/4561571
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

IL-17-Expressing CD4+ and CD8+ T Lymphocytes in Human Toxoplasmosis
by: Jéssica Líver Alves Silva, et al.
Published: (2014-01-01)

HLA‐DR⁺ Tumor Cells Show an Association with a Distinct Immune Microenvironment and CD8⁺ T‐Cell Exhaustion in HBV‐Associated Hepatocellular Carcinoma
by: Jun‐Qing Chang, et al.
Published: (2025-08-01)

Single-cell analysis reveals XCL1+ CD8+ T cells as a therapeutic target in hepatocellular carcinoma
by: Guowei Li, et al.
Published: (2025-12-01)

Percentages of CD4+CD161+ and CD4−CD8−CD161+ T Cells in the Synovial Fluid Are Correlated with Disease Activity in Rheumatoid Arthritis
by: Jinlin Miao, et al.
Published: (2015-01-01)

Association of Absolute Lymphocyte Count and Circulating CD4+ and CD8+ T-Cells with Positive Clinical Outcome in Survivors of Cancer: An Observational Study
by: Suresh Rao, et al.
Published: (2019-07-01)

Immunohistochemical analysis of PD-L1, CD4, CD8, CD20, and PU.1 expression in a dedifferentiated chondrosarcoma: the clinical and prognostic value
by: Olga V. Kovaleva, et al.
Published: (2025-07-01)

Rabies vaccination induces a CD4+ TEM and CD4+CD8+ TEMRA TH1 phenotype in dogs.
by: Haeree P Lang, et al.
Published: (2025-01-01)

CD24 recruits tumor-associated neutrophils to promote the progression of hepatocellular carcinoma
by: Jun Wang, et al.
Published: (2025-08-01)

Patients with ankylosing spondylitis present a distinct CD8 T cell subset with osteogenic and cytotoxic potential
by: Adrian Ciurea, et al.
Published: (2024-02-01)

Assessment of CD4<sup>+</sup> cells subpopulations with the expressing CD39 and CD73 ectonucleotidases in children with psoriasis
by: D. G. Kuptsova, et al.
Published: (2022-07-01)

Hvem diskuterer politikk? - Et longitudinelt perspektiv
by: Ragnar Waldahl
Published: (2015-03-01)

CYTOTOXIC ACTIVITY OF DENDRITIC CELLS AGAINST ACTIVATED CD4+ AND CD8+T-LYMPHOCYTES IN THE CULTURE IN VITRO
by: T. V. Tyrinova, et al.
Published: (2012-05-01)

CD4+ but not CD8+ T cells are required for protection against severe guinea pig cytomegalovirus infections.
by: Tyler B Rollman, et al.
Published: (2024-11-01)

Depletion of conventional CD4+ T cells is required for robust priming and dissemination of tumor antigen-specific CD8+ T cells in the setting of anti-CD4 therapy
by: Keisuke Shirai, et al.
Published: (2024-11-01)

Role of CD133 antibody-conjugated nanocarrier in enhancing the targetability of hepatocellular carcinoma stem cells
by: Hadeer A. Aglan, et al.
Published: (2025-08-01)

The Influence of the Coexpression of CD4 and CD8 in Cutaneous Lesions on Prognosis of Mycosis Fungoides: A Preliminary Study
by: Sergio Umberto De Marchi, et al.
Published: (2014-01-01)

Expression of scavenger receptors CD163, CD204, and CD206 on macrophages in patients with pulmonary tuberculosis
by: E. G. Churina, et al.
Published: (2023-01-01)

Infiltration of CD3+ and CD8+ lymphocytes in association with inflammation and survival in pancreatic cancer.
by: Gerik W Tushoski-Alemán, et al.
Published: (2024-01-01)

Samfunnsforskningen er relevant men for hva og hvem?
by: ANNE BREGNBALLE, et al.
Published: (2012-02-01)

CD4+/CD8+ lymphocyte ratio as a biomarker of morbidity and severity in patients with moderate and severe COVID-19
by: D. Torres-Gonzales, et al.
Published: (2025-07-01)

Hesperidin Inhibits Inflammatory Response Induced by Aeromonas hydrophila Infection and Alters CD4+/CD8+ T Cell Ratio
by: Abdelaziz S. A. Abuelsaad, et al.
Published: (2014-01-01)

Intestinal CD4−CD8αβ−TCRαβ+ T cells function as tolerogenic antigen presenting cells in mice
by: Yasuhiro Nemoto, et al.
Published: (2025-08-01)

Gzmk+ CD8 T cells in inflammatory diseases
by: Cui Xin, et al.
Published: (2025-08-01)

ANALYSIS OF CONTROL MEASUREMENTS OF «T-CELL REPLICATES» AND «T-CELL SUMMARY» IN INVESTIGATION OF THE IMMUNE STATUS OF HIV-INFECTED PATIENTS AND DETECTION DOUBLE NEGATIVE SUBPOPULATION OF T-LYMPHOCYTES (CD45+CD3+CD4–CD8–)
by: E. V. Shestakova, et al.
Published: (2014-07-01)

The size of CD8+ infiltrating T cells is a prognostic marker for esophageal squamous cell carcinoma
by: Kengo Shigehara, et al.
Published: (2025-07-01)

CD4/CD8 T-cell ratio in bronchoalveolar lavage fluid as a marker of sarcoidosis severity: a retrospective study
by: Thibaut Zannese, et al.
Published: (2025-05-01)

MEK inhibition prevents human skin graft rejection by promoting CD8+TCF1+ over CD8 effector T cells
by: Christine Chauveau, et al.
Published: (2025-09-01)

Differential quantities of immune checkpoint-expressing CD8 T cells in soft tissue sarcoma subtypes
by: Cornelis Verhoef, et al.
Published: (2020-10-01)

Expression and significance of platelet GPIb alpha,CD62P and CD63 in maintenance haemodialysis patients
by: LUO Min-hong, et al.
Published: (2018-01-01)

Bioactivity of Purple Yam Tuber (Dioscorea alata L.) on the Level of CD8+and CD8+CD462L+ T cells and Histology of Liver in BALB/c Mice Model of Digestive Allergy
by: Yuyun Ika Christina, et al.
Published: (2014-12-01)

Lesões bucais manifestadas em pacientes aidéticos e tuberculosos, relacionadas com a contagem celular cd4+ / cd8+
by: Maurício Roth Volkweis, et al.
Published: (2010-07-01)

Development and validation of a CD4+/CD8+ ratio-based nomogram to predict plastic bronchitis in pediatric Mycoplasma pneumoniae pneumonia
by: Di Lian, et al.
Published: (2025-07-01)

Adenosine metabolic signature in circulating CD4+ T cells predicts remission in rheumatoid arthritis
by: Dennis W Lendrem, et al.
Published: (2024-02-01)

Intratumoral CD8+ tumor-infiltrating lymphocytes as prognostic predictors in radio-chemoradiotherapy-treated nasopharyngeal carcinoma
by: Xinjing Li, et al.
Published: (2025-05-01)

CD73 is dispensable for the regulation of inflationary CD8+ T-cells after murine cytomegalovirus infection and adenovirus immunisation.
by: Stuart Sims, et al.
Published: (2014-01-01)

Engineering safe anti-CD19-CD28ζ CAR T cells with CD8a hinge domain in serum-free media for adoptive immunotherapy
by: Muthuganesh Muthuvel, et al.
Published: (2025-05-01)

Prognostic significance of CD163- and CD68-expressing macrophages in nodular sclerosis Hodgkin lymphoma
by: E. A. Perfilova, et al.
Published: (2022-01-01)

Dynamics of subpopulations of CD15<sup>+</sup>CD66b<sup>+</sup> and CD62L<sup>+</sup>CD63<sup>+</sup> circulating neutrophils in patients with benign neoplasms and progression of kidney cancer
by: I. R. Myagdieva, et al.
Published: (2025-06-01)

Identification of disulfidptosis-related prognostic biomarkers associated with CD4 + and CD8 + T cells infiltration for sarcoma by integrating bioinformatic analysis and experimental validation
by: Wenliang Tan, et al.
Published: (2025-07-01)

Mobilization of CD4+, CD8+, and B220+ on Broiler Chicken Spleen with Feed Contained Polyscias obtusa Post Infection of Salmonella typhimurium
by: Andi Rizki A, Pradana, et al.
Published: (2013-06-01)