Case report: A rare case of intragastric metastasis after liver transplantation for liver cancer

A 13-year-old boy was admitted to Xiang’an Hospital of Xiamen University due to HBV-related liver cancer. Intrahepatic metastasis was considered to occur by CT scan. A gastroscope revealed esophagogastric variceal bleeding, and later, the patient underwent a successful liver transplantation. Fourtee...

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Main Authors: Youfeng Xue, Baojie Shi, Jianfa Zhong, Guimei Wang, Jie Wang, Wenbin An, Yunyun Qian, Zhaojie Su, Zhihai Peng, Hao Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1495517/full
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author Youfeng Xue
Baojie Shi
Jianfa Zhong
Guimei Wang
Jie Wang
Wenbin An
Yunyun Qian
Zhaojie Su
Zhihai Peng
Hao Li
author_facet Youfeng Xue
Baojie Shi
Jianfa Zhong
Guimei Wang
Jie Wang
Wenbin An
Yunyun Qian
Zhaojie Su
Zhihai Peng
Hao Li
author_sort Youfeng Xue
collection DOAJ
description A 13-year-old boy was admitted to Xiang’an Hospital of Xiamen University due to HBV-related liver cancer. Intrahepatic metastasis was considered to occur by CT scan. A gastroscope revealed esophagogastric variceal bleeding, and later, the patient underwent a successful liver transplantation. Fourteen months posttransplant, chest CT indicated lung metastasis, and the patient underwent thoracoscopic radical resection of lung cancer. Twenty-one months posttransplant, gastroscopy revealed a gastric fundus tumor growing into the gastric cavity. Proximal gastrectomy was performed, and pathology indicated moderately to poorly differentiated carcinoma without invasion of serosa, suggesting the first study to report HCC metastasis to the stomach lumen without invasion of serosa after LT. Currently, the alpha-fetoprotein (AFP) level of the patient has dropped below normal.
format Article
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institution Kabale University
issn 2234-943X
language English
publishDate 2024-12-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Oncology
spelling doaj-art-0739024ce4c64d24aa4b34227f7c47022024-12-06T05:10:20ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2024-12-011410.3389/fonc.2024.14955171495517Case report: A rare case of intragastric metastasis after liver transplantation for liver cancerYoufeng Xue0Baojie Shi1Jianfa Zhong2Guimei Wang3Jie Wang4Wenbin An5Yunyun Qian6Zhaojie Su7Zhihai Peng8Hao Li9Hepatobiliary Surgery Department, Fuqing Hospital, Fuzhou, Fujian, ChinaOrgan Transplantation Clinical Medical Center of Xiamen University, Department of Organ Transplantation, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, ChinaOrgan Transplantation Clinical Medical Center of Xiamen University, Department of Organ Transplantation, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, ChinaOrgan Transplantation Clinical Medical Center of Xiamen University, Department of Organ Transplantation, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, ChinaOrgan Transplantation Clinical Medical Center of Xiamen University, Department of Organ Transplantation, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, ChinaOrgan Transplantation Clinical Medical Center of Xiamen University, Department of Organ Transplantation, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, ChinaOrgan Transplantation Clinical Medical Center of Xiamen University, Department of Organ Transplantation, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, ChinaOrgan Transplantation Clinical Medical Center of Xiamen University, Department of Organ Transplantation, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, ChinaOrgan Transplantation Clinical Medical Center of Xiamen University, Department of Organ Transplantation, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, ChinaOrgan Transplantation Clinical Medical Center of Xiamen University, Department of Organ Transplantation, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, ChinaA 13-year-old boy was admitted to Xiang’an Hospital of Xiamen University due to HBV-related liver cancer. Intrahepatic metastasis was considered to occur by CT scan. A gastroscope revealed esophagogastric variceal bleeding, and later, the patient underwent a successful liver transplantation. Fourteen months posttransplant, chest CT indicated lung metastasis, and the patient underwent thoracoscopic radical resection of lung cancer. Twenty-one months posttransplant, gastroscopy revealed a gastric fundus tumor growing into the gastric cavity. Proximal gastrectomy was performed, and pathology indicated moderately to poorly differentiated carcinoma without invasion of serosa, suggesting the first study to report HCC metastasis to the stomach lumen without invasion of serosa after LT. Currently, the alpha-fetoprotein (AFP) level of the patient has dropped below normal.https://www.frontiersin.org/articles/10.3389/fonc.2024.1495517/fullhepatocellular carcinomaintragastric metastasisliver cancerliver transplantationpediatric liver transplantation
spellingShingle Youfeng Xue
Baojie Shi
Jianfa Zhong
Guimei Wang
Jie Wang
Wenbin An
Yunyun Qian
Zhaojie Su
Zhihai Peng
Hao Li
Case report: A rare case of intragastric metastasis after liver transplantation for liver cancer
Frontiers in Oncology
hepatocellular carcinoma
intragastric metastasis
liver cancer
liver transplantation
pediatric liver transplantation
title Case report: A rare case of intragastric metastasis after liver transplantation for liver cancer
title_full Case report: A rare case of intragastric metastasis after liver transplantation for liver cancer
title_fullStr Case report: A rare case of intragastric metastasis after liver transplantation for liver cancer
title_full_unstemmed Case report: A rare case of intragastric metastasis after liver transplantation for liver cancer
title_short Case report: A rare case of intragastric metastasis after liver transplantation for liver cancer
title_sort case report a rare case of intragastric metastasis after liver transplantation for liver cancer
topic hepatocellular carcinoma
intragastric metastasis
liver cancer
liver transplantation
pediatric liver transplantation
url https://www.frontiersin.org/articles/10.3389/fonc.2024.1495517/full
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