Depth-corrected multi-factor dissection of chromatin accessibility for scATAC-seq data with PACS
Abstract Single cell ATAC-seq (scATAC-seq) experimental designs have become increasingly complex, with multiple factors that might affect chromatin accessibility, including genotype, cell type, tissue of origin, sample location, batch, etc., whose compound effects are difficult to test by existing m...
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Main Authors: | Zhen Miao, Jianqiao Wang, Kernyu Park, Da Kuang, Junhyong Kim |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-55580-5 |
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