Adhesin RadD: the secret weapon of Fusobacterium nucleatum
Fusobacterium nucleatum can promote colorectal cancer (CRC) development through a variety of virulence proteins. Zhang et al. recently identified an adhesin RadD, for Fusobacterium nucleatum adhesion to CRC. Targeting the interaction between RadD and CD147 will provide a new strategy for CRC treatme...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Gut Microbes |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/19490976.2024.2426617 |
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| _version_ | 1846172566553624576 |
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| author | Dingjiacheng Jia Shujie Chen |
| author_facet | Dingjiacheng Jia Shujie Chen |
| author_sort | Dingjiacheng Jia |
| collection | DOAJ |
| description | Fusobacterium nucleatum can promote colorectal cancer (CRC) development through a variety of virulence proteins. Zhang et al. recently identified an adhesin RadD, for Fusobacterium nucleatum adhesion to CRC. Targeting the interaction between RadD and CD147 will provide a new strategy for CRC treatment. This Commentary and View not only summarizes the research highlights but also discusses the possibility of targeted clearance of Fusobacterium nucleatum in clinical applications. |
| format | Article |
| id | doaj-art-0720ad72880e4aa09b7703677f6f4ff8 |
| institution | Kabale University |
| issn | 1949-0976 1949-0984 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Gut Microbes |
| spelling | doaj-art-0720ad72880e4aa09b7703677f6f4ff82024-11-09T19:34:16ZengTaylor & Francis GroupGut Microbes1949-09761949-09842024-12-0116110.1080/19490976.2024.2426617Adhesin RadD: the secret weapon of Fusobacterium nucleatumDingjiacheng Jia0Shujie Chen1Department of Gastroenterology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, ChinaInstitution of Gastroenterology, Zhejiang University, Hangzhou, Zhejiang Province, ChinaFusobacterium nucleatum can promote colorectal cancer (CRC) development through a variety of virulence proteins. Zhang et al. recently identified an adhesin RadD, for Fusobacterium nucleatum adhesion to CRC. Targeting the interaction between RadD and CD147 will provide a new strategy for CRC treatment. This Commentary and View not only summarizes the research highlights but also discusses the possibility of targeted clearance of Fusobacterium nucleatum in clinical applications.https://www.tandfonline.com/doi/10.1080/19490976.2024.2426617AdhesinCD147colorectal cancerfusobacterium nucleatumgut microbiotaRadD |
| spellingShingle | Dingjiacheng Jia Shujie Chen Adhesin RadD: the secret weapon of Fusobacterium nucleatum Gut Microbes Adhesin CD147 colorectal cancer fusobacterium nucleatum gut microbiota RadD |
| title | Adhesin RadD: the secret weapon of Fusobacterium nucleatum |
| title_full | Adhesin RadD: the secret weapon of Fusobacterium nucleatum |
| title_fullStr | Adhesin RadD: the secret weapon of Fusobacterium nucleatum |
| title_full_unstemmed | Adhesin RadD: the secret weapon of Fusobacterium nucleatum |
| title_short | Adhesin RadD: the secret weapon of Fusobacterium nucleatum |
| title_sort | adhesin radd the secret weapon of fusobacterium nucleatum |
| topic | Adhesin CD147 colorectal cancer fusobacterium nucleatum gut microbiota RadD |
| url | https://www.tandfonline.com/doi/10.1080/19490976.2024.2426617 |
| work_keys_str_mv | AT dingjiachengjia adhesinraddthesecretweaponoffusobacteriumnucleatum AT shujiechen adhesinraddthesecretweaponoffusobacteriumnucleatum |