Immune response profiling of HERV-W envelope proteins in multiple sclerosis: potential biomarkers for disease progression

Immune response profiling of HERV-W envelope proteins in multiple sclerosis: potential biomarkers for disease progression

IntroductionThe envelope proteins syncytin-1 and pHERV-W from the Human Endogenous Retroviral family ‘W’ (HERV-W) have been identified as potential risk factors in multiple sclerosis (MS). This study aims to evaluate both humoral and cell-mediated immune response to antigenic peptides derived from t...

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Bibliographic Details
Main Authors: Stefano Ruberto, María I. Domınguez-Mozo, M. Angel Garcıa-Martınez, Davide Cossu, Leonardo A. Sechi, Roberto Alvarez-Lafuente
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
HERV-W
syncytin-1
biomarkers
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1505239/full
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