Treatment with Tau fibrils impact Huntington's disease-related phenotypes in cell and mouse models

Treatment with Tau fibrils impact Huntington's disease-related phenotypes in cell and mouse models

There is now compelling evidence for the presence of pathological forms of Tau in tissues of both patients and animal models of Huntington's disease (HD). While the root cause of this illness is a mutation within the huntingtin gene, a number of studies now suggest that HD could also be conside...

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Bibliographic Details
Main Authors: Shireen Salem, Melanie Alpaugh, Martine Saint-Pierre, Flavia Natale Alves-Martins-Borba, Catalina Cerquera-Cleves, Mado Lemieux, Soki Bradel Ngonza-Nito, Paul De Koninck, Ronald Melki, Francesca Cicchetti
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Neurobiology of Disease
Subjects:
Mutant huntingtin protein
Huntingtin aggregation
zQ175
Animal behavior
Heat shock proteins
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996124002961
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