Effect of Soy Isoflavone on Prostate Cancer Cell Apoptosis Through Inhibition of STAT3, ERK, and AKT

Effect of Soy Isoflavone on Prostate Cancer Cell Apoptosis Through Inhibition of STAT3, ERK, and AKT

Genistein, an isoflavone found in soybeans, exhibits antioxidant, anti-inflammatory, and anticancer properties. This study explored the molecular mechanisms behind genistein’s anticancer effects in prostate cancer DU145 cells. In this study, genistein decreased cell viability, increased annexin V-PE...

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Bibliographic Details
Main Authors: Yoon-Jin Lee, Changyeol Lee, Dongsic Choi, Yeji Lee, Sang-Han Lee
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Current Issues in Molecular Biology
Subjects:
genistein
prostate cancer
apoptosis
reactive oxygen species
STAT3
Online Access:https://www.mdpi.com/1467-3045/46/11/743
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