Physiopathological effects of entrance versus distal spread-out Bragg peak on mouse spinal cord neurons

Physiopathological effects of entrance versus distal spread-out Bragg peak on mouse spinal cord neurons

Abstract Recent investigations into radiation-induced side effects have focused on understanding the physiopathological consequences of irradiation on late-responding tissues like the spinal cord, which can lead to chronic progressive myelopathy. Proton therapy, an advanced radiation treatment, aims...

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Main Authors: Filippo Torrisi, Francesco Paolo Cammarata, Valentina Bravatà, Marco Calvaruso, Cristiana Alberghina, Anna Maria Pavone, Giada Petringa, Giuseppe Antonio Pablo Cirrone, Simona Denaro, Anna Gervasi, Simona D’Aprile, Nunzio Vicario, Emanuele Scifoni, Pietro Pisciotta, Giorgio Russo, Rosalba Parenti
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Synaptic plasticity
RBE
Radiation-induced off-target effects
Proton therapy
Bragg peak
Online Access:https://doi.org/10.1038/s41598-024-84902-2
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