Enantioselective aza-electrophilic dearomatization of naphthalene derivatives

Abstract The catalytic asymmetric dearomatization of naphthalenes is a pivotal strategy for generating enantioenriched three-dimensional aliphatic polycycles from flat aromatic precursors. However, achieving such transformations involving electronically unbiased naphthalenes remains a long-standing...

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Bibliographic Details
Main Authors: Jun Liu, Haina Liu, Meijuan Zhou, Xiaolong Yu, Gang Zhao, Hongyu Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60660-1
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