GATA1-mediated macrophage polarization via TrkB/cGMP–PKG signaling pathway to promote the development of preeclampsia

GATA1-mediated macrophage polarization via TrkB/cGMP–PKG signaling pathway to promote the development of preeclampsia

Abstract Background Preeclampsia (PE) is a severe pregnancy complication characterized by hypertension and proteinuria. PE poses a substantial threat to the health of both mothers and fetuses, and currently, there is no definitive treatment available. Recent studies have indicated that the transcrip...

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Bibliographic Details
Main Authors: Wushan Li, Fei Hou, Di Cheng, Fengchun Gao, Jin Wang, Baoxia Cui
Format: Article
Language:English
Published: BMC 2025-01-01
Series:European Journal of Medical Research
Subjects:
GATA1
Knockdown
NTRK2
TrkB
cGMP–PKG
Macrophage
Online Access:https://doi.org/10.1186/s40001-024-02229-0
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