Comparison of two graft procedures in a bilateral sinus lift by MRI and histomorphometric analysis: a case report
Magnetic resonance imaging (MRI) was shown to be a viable method for graft healing evaluation. Platelet-rich fibrin (PRF) was found to speed up bone graft healing process. Sinus lift surgery outcomes after healing period are usually performed with computerized tomography that is not capable to descr...
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EDP Sciences
2024-01-01
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| Series: | Journal of Oral Medicine and Oral Surgery |
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| Online Access: | https://www.jomos.org/articles/mbcb/full_html/2024/03/mbcb240060/mbcb240060.html |
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| author | Maglione Michele Michelon Filippo Bevilacqua Lorenzo Bertolotto Michele Rothweiler René |
| author_facet | Maglione Michele Michelon Filippo Bevilacqua Lorenzo Bertolotto Michele Rothweiler René |
| author_sort | Maglione Michele |
| collection | DOAJ |
| description | Magnetic resonance imaging (MRI) was shown to be a viable method for graft healing evaluation. Platelet-rich fibrin (PRF) was found to speed up bone graft healing process. Sinus lift surgery outcomes after healing period are usually performed with computerized tomography that is not capable to describe graft vascularization and exposes patient to ionizing radiation. The objective of this study is to propose contrast-enhanced magnetic resonance imaging (CE-MRI) as a promising method for the in vivo assessment of sinus lift grafting procedures. A bilateral sinus augmentation surgery was performed. Left sinus was grafted only with bovine deproteinized bone mixed in a 1:1 ratio with autologous bone, in the right sinus, the same biomaterials with the addition of platelet-rich fibrin (PRF) were applied. CE-MRI was performed to evaluate angiogenesis before surgery and at 11, 25, 53, and 104 days after surgery. At 6 months (T0) and after 10 years (T1), before dental implants insertion, bone biopsies were performed and analysed quantitatively. Left sinus graft showed a centripetal pattern of angiogenesis, with the central region remaining unvascularized at 104 days post-surgery. Right side showed a wider and homogeneous vascularization from 25 days after surgery. At T0 new bone formation was only peripheral in the left sinus, whereas it developed both peripherally and through biomaterial in the right sinus. At T1 particles of biomaterial were still present in left sinus, while in right sinus they were not. CE-MRI offers quantitative parameters to evaluate vascularization of biomaterials. The addition of PRF promotes an early development of a widespread vascular system. |
| format | Article |
| id | doaj-art-06670af710214d46a39ce3487439ca69 |
| institution | Kabale University |
| issn | 2608-1326 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | Journal of Oral Medicine and Oral Surgery |
| spelling | doaj-art-06670af710214d46a39ce3487439ca692025-01-08T11:11:54ZengEDP SciencesJournal of Oral Medicine and Oral Surgery2608-13262024-01-013032110.1051/mbcb/2024022mbcb240060Comparison of two graft procedures in a bilateral sinus lift by MRI and histomorphometric analysis: a case reportMaglione Michele0Michelon Filippo1Bevilacqua Lorenzo2Bertolotto Michele3Rothweiler René4School of Dental Sciences, Department of Medical, Surgical and Health Sciences, University of TriesteSchool of Dental Sciences, Department of Medical, Surgical and Health Sciences, University of TriesteSchool of Dental Sciences, Department of Medical, Surgical and Health Sciences, University of TriesteDepartment of Radiology, Cattinara Hospital, University of TriesteDepartment of Oral and Craniomaxillofacial Surgery, University Hospital FreiburgMagnetic resonance imaging (MRI) was shown to be a viable method for graft healing evaluation. Platelet-rich fibrin (PRF) was found to speed up bone graft healing process. Sinus lift surgery outcomes after healing period are usually performed with computerized tomography that is not capable to describe graft vascularization and exposes patient to ionizing radiation. The objective of this study is to propose contrast-enhanced magnetic resonance imaging (CE-MRI) as a promising method for the in vivo assessment of sinus lift grafting procedures. A bilateral sinus augmentation surgery was performed. Left sinus was grafted only with bovine deproteinized bone mixed in a 1:1 ratio with autologous bone, in the right sinus, the same biomaterials with the addition of platelet-rich fibrin (PRF) were applied. CE-MRI was performed to evaluate angiogenesis before surgery and at 11, 25, 53, and 104 days after surgery. At 6 months (T0) and after 10 years (T1), before dental implants insertion, bone biopsies were performed and analysed quantitatively. Left sinus graft showed a centripetal pattern of angiogenesis, with the central region remaining unvascularized at 104 days post-surgery. Right side showed a wider and homogeneous vascularization from 25 days after surgery. At T0 new bone formation was only peripheral in the left sinus, whereas it developed both peripherally and through biomaterial in the right sinus. At T1 particles of biomaterial were still present in left sinus, while in right sinus they were not. CE-MRI offers quantitative parameters to evaluate vascularization of biomaterials. The addition of PRF promotes an early development of a widespread vascular system.https://www.jomos.org/articles/mbcb/full_html/2024/03/mbcb240060/mbcb240060.htmlmaxillary sinusmagnetic resonance imagingbone substitutes |
| spellingShingle | Maglione Michele Michelon Filippo Bevilacqua Lorenzo Bertolotto Michele Rothweiler René Comparison of two graft procedures in a bilateral sinus lift by MRI and histomorphometric analysis: a case report Journal of Oral Medicine and Oral Surgery maxillary sinus magnetic resonance imaging bone substitutes |
| title | Comparison of two graft procedures in a bilateral sinus lift by MRI and histomorphometric analysis: a case report |
| title_full | Comparison of two graft procedures in a bilateral sinus lift by MRI and histomorphometric analysis: a case report |
| title_fullStr | Comparison of two graft procedures in a bilateral sinus lift by MRI and histomorphometric analysis: a case report |
| title_full_unstemmed | Comparison of two graft procedures in a bilateral sinus lift by MRI and histomorphometric analysis: a case report |
| title_short | Comparison of two graft procedures in a bilateral sinus lift by MRI and histomorphometric analysis: a case report |
| title_sort | comparison of two graft procedures in a bilateral sinus lift by mri and histomorphometric analysis a case report |
| topic | maxillary sinus magnetic resonance imaging bone substitutes |
| url | https://www.jomos.org/articles/mbcb/full_html/2024/03/mbcb240060/mbcb240060.html |
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