Immunohistochemical expression of vascular endothelial growth factor in orofacial lesions – A review

Angiogenesis is considered to be an important biological process in disease progression and tumorigenesis. Among the various factors associated with angiogenesis, vascular endothelial growth factor (VEGF) is a leading candidate. VEGF induces the proliferation, differentiation, and migration of vascu...

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Main Authors: Bhavana Gupta, Shaleen Chandra, Vineet Raj, Vivek Gupta
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Journal of Oral Biology and Craniofacial Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221242681600021X
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author Bhavana Gupta
Shaleen Chandra
Vineet Raj
Vivek Gupta
author_facet Bhavana Gupta
Shaleen Chandra
Vineet Raj
Vivek Gupta
author_sort Bhavana Gupta
collection DOAJ
description Angiogenesis is considered to be an important biological process in disease progression and tumorigenesis. Among the various factors associated with angiogenesis, vascular endothelial growth factor (VEGF) is a leading candidate. VEGF induces the proliferation, differentiation, and migration of vascular endothelial cells, increases capillary permeability, and enhances endothelial cell survival by preventing apoptosis. This article reviews and highlights the role of VEGF in health, and various oral diseases.
format Article
id doaj-art-065aeec0f8774d39a40e49abf7342a04
institution Kabale University
issn 2212-4268
language English
publishDate 2016-09-01
publisher Elsevier
record_format Article
series Journal of Oral Biology and Craniofacial Research
spelling doaj-art-065aeec0f8774d39a40e49abf7342a042024-11-23T06:27:01ZengElsevierJournal of Oral Biology and Craniofacial Research2212-42682016-09-0163231236Immunohistochemical expression of vascular endothelial growth factor in orofacial lesions – A reviewBhavana Gupta0Shaleen Chandra1Vineet Raj2Vivek Gupta3Senior Lecturer, Department of Oral Pathology, Rama Dental College, Kanpur, U.P., India; Corresponding author.Professor and Head, Department of Oral Pathology, King George's Medical University, Lucknow, IndiaAssociate Professor, Department of Oral Pathology, Chandra Dental College, Lucknow, U.P., IndiaProfessor, Department of Periodontology, Rama Dental College and Hospital, Kanpur, IndiaAngiogenesis is considered to be an important biological process in disease progression and tumorigenesis. Among the various factors associated with angiogenesis, vascular endothelial growth factor (VEGF) is a leading candidate. VEGF induces the proliferation, differentiation, and migration of vascular endothelial cells, increases capillary permeability, and enhances endothelial cell survival by preventing apoptosis. This article reviews and highlights the role of VEGF in health, and various oral diseases.http://www.sciencedirect.com/science/article/pii/S221242681600021XOral diseasesOral cancerAngiogenesisVascular endothelial growth factor (VEGF)Oral squamous cell carcinoma (OSCC)
spellingShingle Bhavana Gupta
Shaleen Chandra
Vineet Raj
Vivek Gupta
Immunohistochemical expression of vascular endothelial growth factor in orofacial lesions – A review
Journal of Oral Biology and Craniofacial Research
Oral diseases
Oral cancer
Angiogenesis
Vascular endothelial growth factor (VEGF)
Oral squamous cell carcinoma (OSCC)
title Immunohistochemical expression of vascular endothelial growth factor in orofacial lesions – A review
title_full Immunohistochemical expression of vascular endothelial growth factor in orofacial lesions – A review
title_fullStr Immunohistochemical expression of vascular endothelial growth factor in orofacial lesions – A review
title_full_unstemmed Immunohistochemical expression of vascular endothelial growth factor in orofacial lesions – A review
title_short Immunohistochemical expression of vascular endothelial growth factor in orofacial lesions – A review
title_sort immunohistochemical expression of vascular endothelial growth factor in orofacial lesions a review
topic Oral diseases
Oral cancer
Angiogenesis
Vascular endothelial growth factor (VEGF)
Oral squamous cell carcinoma (OSCC)
url http://www.sciencedirect.com/science/article/pii/S221242681600021X
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AT vineetraj immunohistochemicalexpressionofvascularendothelialgrowthfactorinorofaciallesionsareview
AT vivekgupta immunohistochemicalexpressionofvascularendothelialgrowthfactorinorofaciallesionsareview