Effects of different forms of amino acid supplementation on the performance and intestinal barrier function of laying hens fed a low-protein diet

ABSTRACT: The aim of this study was to investigate the effects of low-protein diets and the sustained release of synthetic amino acids (AA) on the performance, intestinal barrier function and nitrogen excretion of laying hens. Two hundred eighty-eight 39-week-old Hyline brown laying hens of were ran...

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Main Authors: Hui Liu, Kangqi Xu, Huimin Wang, Hai Lin, Xiaoyan Yang, Xiaojuan Wang, Jingpeng Zhao, Baishun Ma, Quanxian Shu, Yanbo Lu, Hongchao Jiao
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Poultry Science
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Online Access:http://www.sciencedirect.com/science/article/pii/S0032579124009532
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author Hui Liu
Kangqi Xu
Huimin Wang
Hai Lin
Xiaoyan Yang
Xiaojuan Wang
Jingpeng Zhao
Baishun Ma
Quanxian Shu
Yanbo Lu
Hongchao Jiao
author_facet Hui Liu
Kangqi Xu
Huimin Wang
Hai Lin
Xiaoyan Yang
Xiaojuan Wang
Jingpeng Zhao
Baishun Ma
Quanxian Shu
Yanbo Lu
Hongchao Jiao
author_sort Hui Liu
collection DOAJ
description ABSTRACT: The aim of this study was to investigate the effects of low-protein diets and the sustained release of synthetic amino acids (AA) on the performance, intestinal barrier function and nitrogen excretion of laying hens. Two hundred eighty-eight 39-week-old Hyline brown laying hens of were randomly divided into 3 groups with 8 replicates per group. The crude protein level in the control group (CON) was 16%, the crude protein levels in the crystal AA supplement group (LCP-CAA) and microencapsulated AA group (LCP-MAA) were both 13%, and the AA levels in the LCP-CAA and LCP-MAA groups were consistent with that in the CON group. The experiment lasted 12 wk, and production performance was assessed weekly. The FCR and ADFI values were significantly greater for the LCP-CAA group than for the CON and LCP-MAA groups (P < 0.05). Two hours after feeding, His levels were significantly greater in the LCP-CAA group than in the LCP-MAA group (P < 0.05); 4 h after feeding, the contents of Met, Thr, Leu and Val were significantly greater in blood from the LCP-MAA group (P < 0.05); 6 h after feeding, Trp, Ile and Arg levels were significantly greater in the LCP-MAA group (P < 0.05). The chylase content significantly decreased in the duodenum of the LCP-CAA group (P < 0.05), and the chylase and trypsin were contents increased in the ileum of the LCP-MAA group (P < 0.05). In the LCP-MAA group, significantly increased mRNA expression levels of Occludin, ZO-1 in duodenum; Occludin, ZO-1, y+LAT1 in jejunum; and ZO-1 in ileum were detected at 8 and 12 weeks (P < 0.05). The fecal nitrogen content significantly decreased in the low protein diet group (P < 0.01). In conclusion, reducing dietary crude protein levels and supplementing with microencapsulated AAs can improve intestinal barrier function, promote digestive enzyme secretion, increase the expression of AA transporters, improve dietary protein utilization efficiency, and reduce nitrogen emission in laying hens.
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spelling doaj-art-0621a82170b0400e9afb9ca7467f4c5d2024-12-14T06:29:04ZengElsevierPoultry Science0032-57912024-12-0110312104375Effects of different forms of amino acid supplementation on the performance and intestinal barrier function of laying hens fed a low-protein dietHui Liu0Kangqi Xu1Huimin Wang2Hai Lin3Xiaoyan Yang4Xiaojuan Wang5Jingpeng Zhao6Baishun Ma7Quanxian Shu8Yanbo Lu9Hongchao Jiao10Department of Animal Science, Shandong Agricultural University, Key Laboratory of Efficient Utilization of Non-grain Feed Resources (Co-construction by Ministry and Province), Shandong Provincial Key Laboratory of Animal Nutrition and Efficient Feeding, Taian 271018, Shandong Province, China; Animal Husbandry and Veterinary Service Center of Xintai City, Xintai 271200, Shandong Province, ChinaDepartment of Animal Science, Shandong Agricultural University, Key Laboratory of Efficient Utilization of Non-grain Feed Resources (Co-construction by Ministry and Province), Shandong Provincial Key Laboratory of Animal Nutrition and Efficient Feeding, Taian 271018, Shandong Province, ChinaDepartment of Animal Science, Shandong Agricultural University, Key Laboratory of Efficient Utilization of Non-grain Feed Resources (Co-construction by Ministry and Province), Shandong Provincial Key Laboratory of Animal Nutrition and Efficient Feeding, Taian 271018, Shandong Province, ChinaDepartment of Animal Science, Shandong Agricultural University, Key Laboratory of Efficient Utilization of Non-grain Feed Resources (Co-construction by Ministry and Province), Shandong Provincial Key Laboratory of Animal Nutrition and Efficient Feeding, Taian 271018, Shandong Province, ChinaShandong Bohi Industry Co. Ltd., Binzhou 256599, Shandong Province, ChinaDepartment of Animal Science, Shandong Agricultural University, Key Laboratory of Efficient Utilization of Non-grain Feed Resources (Co-construction by Ministry and Province), Shandong Provincial Key Laboratory of Animal Nutrition and Efficient Feeding, Taian 271018, Shandong Province, ChinaDepartment of Animal Science, Shandong Agricultural University, Key Laboratory of Efficient Utilization of Non-grain Feed Resources (Co-construction by Ministry and Province), Shandong Provincial Key Laboratory of Animal Nutrition and Efficient Feeding, Taian 271018, Shandong Province, ChinaShandong Xiandai Research Institute of Egg-laying Industry, Shandong Hemeihua Nongmu Co. Ltd., Jinan 250102, Shandong Province, ChinaShandong Bohi Industry Co. Ltd., Binzhou 256599, Shandong Province, ChinaShandong Bohi Industry Co. Ltd., Binzhou 256599, Shandong Province, ChinaDepartment of Animal Science, Shandong Agricultural University, Key Laboratory of Efficient Utilization of Non-grain Feed Resources (Co-construction by Ministry and Province), Shandong Provincial Key Laboratory of Animal Nutrition and Efficient Feeding, Taian 271018, Shandong Province, China; Corresponding author:ABSTRACT: The aim of this study was to investigate the effects of low-protein diets and the sustained release of synthetic amino acids (AA) on the performance, intestinal barrier function and nitrogen excretion of laying hens. Two hundred eighty-eight 39-week-old Hyline brown laying hens of were randomly divided into 3 groups with 8 replicates per group. The crude protein level in the control group (CON) was 16%, the crude protein levels in the crystal AA supplement group (LCP-CAA) and microencapsulated AA group (LCP-MAA) were both 13%, and the AA levels in the LCP-CAA and LCP-MAA groups were consistent with that in the CON group. The experiment lasted 12 wk, and production performance was assessed weekly. The FCR and ADFI values were significantly greater for the LCP-CAA group than for the CON and LCP-MAA groups (P < 0.05). Two hours after feeding, His levels were significantly greater in the LCP-CAA group than in the LCP-MAA group (P < 0.05); 4 h after feeding, the contents of Met, Thr, Leu and Val were significantly greater in blood from the LCP-MAA group (P < 0.05); 6 h after feeding, Trp, Ile and Arg levels were significantly greater in the LCP-MAA group (P < 0.05). The chylase content significantly decreased in the duodenum of the LCP-CAA group (P < 0.05), and the chylase and trypsin were contents increased in the ileum of the LCP-MAA group (P < 0.05). In the LCP-MAA group, significantly increased mRNA expression levels of Occludin, ZO-1 in duodenum; Occludin, ZO-1, y+LAT1 in jejunum; and ZO-1 in ileum were detected at 8 and 12 weeks (P < 0.05). The fecal nitrogen content significantly decreased in the low protein diet group (P < 0.01). In conclusion, reducing dietary crude protein levels and supplementing with microencapsulated AAs can improve intestinal barrier function, promote digestive enzyme secretion, increase the expression of AA transporters, improve dietary protein utilization efficiency, and reduce nitrogen emission in laying hens.http://www.sciencedirect.com/science/article/pii/S0032579124009532laying henlow-protein dietsynthetic amino acidproduction performanceintestinal barrier
spellingShingle Hui Liu
Kangqi Xu
Huimin Wang
Hai Lin
Xiaoyan Yang
Xiaojuan Wang
Jingpeng Zhao
Baishun Ma
Quanxian Shu
Yanbo Lu
Hongchao Jiao
Effects of different forms of amino acid supplementation on the performance and intestinal barrier function of laying hens fed a low-protein diet
Poultry Science
laying hen
low-protein diet
synthetic amino acid
production performance
intestinal barrier
title Effects of different forms of amino acid supplementation on the performance and intestinal barrier function of laying hens fed a low-protein diet
title_full Effects of different forms of amino acid supplementation on the performance and intestinal barrier function of laying hens fed a low-protein diet
title_fullStr Effects of different forms of amino acid supplementation on the performance and intestinal barrier function of laying hens fed a low-protein diet
title_full_unstemmed Effects of different forms of amino acid supplementation on the performance and intestinal barrier function of laying hens fed a low-protein diet
title_short Effects of different forms of amino acid supplementation on the performance and intestinal barrier function of laying hens fed a low-protein diet
title_sort effects of different forms of amino acid supplementation on the performance and intestinal barrier function of laying hens fed a low protein diet
topic laying hen
low-protein diet
synthetic amino acid
production performance
intestinal barrier
url http://www.sciencedirect.com/science/article/pii/S0032579124009532
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