Potential candidates from a functional food Zanthoxyli Pericarpium (Sichuan pepper) for the management of hyperuricemia: high-through virtual screening, network pharmacology and dynamics simulations

Potential candidates from a functional food Zanthoxyli Pericarpium (Sichuan pepper) for the management of hyperuricemia: high-through virtual screening, network pharmacology and dynamics simulations

IntroductionHyperuricemia (HUA) is a metabolic syndrome caused by purine metabolism disorders. Zanthoxyli Pericarpium (ZP) is a medicinal and food homologous plant, and its ripe peel is used to treat diseases and as a spice for cooking. Some studies have shown that ZP can inhibit the formation of xa...

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Bibliographic Details
Main Authors: Meilin Chen, Xiaomei Chen, Qinghong Chen, Chenyang Chu, Shuxuan Yang, Chuanghai Wu, Yanting You, Andrew Hung, Angela Wei Hong Yang, Xiaomin Sun, Lin Zhou, Xiaoshan Zhao, Hong Li, Yanyan Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Endocrinology
Subjects:
hyperuricemia
Zanthoxylum bungeanum
complementary and alternative medicine
molecular docking
molecular dynamics simulation
medicine and food homologous plant
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1436360/full
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