More powerful dysregulation of Helicobacter pylori East Asian-type CagA on intracellular signalings

More powerful dysregulation of Helicobacter pylori East Asian-type CagA on intracellular signalings

Abstract Background Chronic infection by Helicobacter pylori strains expressing cytotoxin-associated gene A (CagA) are the strongest risk factor for gastric cancer. CagA can be classified into East Asian-type and Western-type (CagAE and CagAW), with CagAE being more closely associated with gastric c...

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Main Authors: Xiaofei Ji, Zekun Sun, Hao Wu, Jianhui Zhang, Shuzhen Liu, Xinying Cao, Bin Wang, Feifan Wang, Ying Zhang, Boqing Li, Jiankai Feng, Huilin Zhao
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Microbiology
Subjects:
Helicobacter pylori
CagA
Transcriptome analysis
Gastric cancer
Hypoxia
Online Access:https://doi.org/10.1186/s12866-024-03619-4
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