A Correlation Study on Serum Biomarker and Biochemical Parameters in Acute Heart Failure with Duration of Hospital Stay among Patients with Acute Heart Failure
Aims and background: Cardiac biomarker like serum N‐terminal pro‐B‐type natriuretic peptide (NT-proBNP) has revolutionized the diagnosis of heart failure and also plays an important role in prognosticating heart failure. Limited data exist in correlating the level of cardiac biomarkers and biochemic...
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| Format: | Article |
| Language: | English |
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Jaypee Brothers Medical Publisher
2024-05-01
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| Series: | Indian Journal of Medical Biochemistry |
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| Online Access: | https://www.ijmb.in/doi/IJMB/pdf/10.5005/jp-journals-10054-0232 |
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| author | Suresh Shiva kumar Rangaswamy Ranga raju Mallikarjun Aradhya Riyaz A Kalaburgi Pavithra Venkateshaiah Sathisha T Gururaja |
| author_facet | Suresh Shiva kumar Rangaswamy Ranga raju Mallikarjun Aradhya Riyaz A Kalaburgi Pavithra Venkateshaiah Sathisha T Gururaja |
| author_sort | Suresh Shiva kumar |
| collection | DOAJ |
| description | Aims and background: Cardiac biomarker like serum N‐terminal pro‐B‐type natriuretic peptide (NT-proBNP) has revolutionized the diagnosis of heart failure and also plays an important role in prognosticating heart failure. Limited data exist in correlating the level of cardiac biomarkers and biochemical parameters with duration of hospital stay in patients with clinical evidence of acute heart failure.
Materials and methods: Our study comprised of 200 inpatients diagnosed with acute heart failure both men and women using convenience sampling method. It is a prospective observational study. The inpatients were from the Department of Cardiology of Shridevi Institute of Medical Sciences and Research Hospital, Tumkur, Karnataka, India. The duration of study was from April 2022 to Sep 2023.
Results: There was a positive correlation observed in serum NT-proBNP and potassium values with the duration of stay in the inpatients with acute heart failure (<i>p</i> < 0.05). Serum NT-proBNP was highly significant over a week stay at hospital with a median value of 4784 pg/mL (<i>p</i> < 0.05).
Conclusion: The current study highlights the role of serum NT-proBNP and potassium ion as biomarker as well as prognostic factor in the morbidity of acute heart failure in patients.
Clinical significance: The estimation of their serum levels may help in early prediction of duration of stay in hospital. |
| format | Article |
| id | doaj-art-05c55833e330408c8541c309734a6639 |
| institution | Kabale University |
| issn | 2456-5164 |
| language | English |
| publishDate | 2024-05-01 |
| publisher | Jaypee Brothers Medical Publisher |
| record_format | Article |
| series | Indian Journal of Medical Biochemistry |
| spelling | doaj-art-05c55833e330408c8541c309734a66392025-01-03T07:49:03ZengJaypee Brothers Medical PublisherIndian Journal of Medical Biochemistry2456-51642024-05-0128244010.5005/jp-journals-10054-02321A Correlation Study on Serum Biomarker and Biochemical Parameters in Acute Heart Failure with Duration of Hospital Stay among Patients with Acute Heart FailureSuresh Shiva kumar0https://orcid.org/0009-0008-0711-4920Rangaswamy Ranga raju1https://orcid.org/0009-0001-6799-8288Mallikarjun Aradhya2Riyaz A Kalaburgi3https://orcid.org/0000-0002-0254-4859Pavithra Venkateshaiah4https://orcid.org/0009-0004-1686-5284Sathisha T Gururaja5https://orcid.org/0000-0002-5998-2657Department of Cardiology, Shridevi Institute of Medical Sciences and Research Hospital, Tumkur, Karnataka, IndiaDepartment of Biochemistry, Mysore Medical College and Research Institute, Mysuru, Karnataka, IndiaDepartment of General Medicine, Shridevi Institute of Medical Sciences and Research Hospital, Tumkur, Karnataka, IndiaDepartment of Community Medicine, Sri Siddhartha Medical College, Tumkur, Karnataka, IndiaDepartment of Clinical Research, Shridevi Institute of Allied Health Sciences, Tumkur, Karnataka, IndiaSathisha Tumkur Gururaja, Department of Biochemistry, Shridevi Institute of Medical Sciences and Research Hospital, Tumkur, Karnataka, India, Phone: +91 9980141537Aims and background: Cardiac biomarker like serum N‐terminal pro‐B‐type natriuretic peptide (NT-proBNP) has revolutionized the diagnosis of heart failure and also plays an important role in prognosticating heart failure. Limited data exist in correlating the level of cardiac biomarkers and biochemical parameters with duration of hospital stay in patients with clinical evidence of acute heart failure. Materials and methods: Our study comprised of 200 inpatients diagnosed with acute heart failure both men and women using convenience sampling method. It is a prospective observational study. The inpatients were from the Department of Cardiology of Shridevi Institute of Medical Sciences and Research Hospital, Tumkur, Karnataka, India. The duration of study was from April 2022 to Sep 2023. Results: There was a positive correlation observed in serum NT-proBNP and potassium values with the duration of stay in the inpatients with acute heart failure (<i>p</i> < 0.05). Serum NT-proBNP was highly significant over a week stay at hospital with a median value of 4784 pg/mL (<i>p</i> < 0.05). Conclusion: The current study highlights the role of serum NT-proBNP and potassium ion as biomarker as well as prognostic factor in the morbidity of acute heart failure in patients. Clinical significance: The estimation of their serum levels may help in early prediction of duration of stay in hospital.https://www.ijmb.in/doi/IJMB/pdf/10.5005/jp-journals-10054-0232acute heart failureduration of stayin-patientsn‐terminal pro‐b‐type natriuretic peptideprospective observational study |
| spellingShingle | Suresh Shiva kumar Rangaswamy Ranga raju Mallikarjun Aradhya Riyaz A Kalaburgi Pavithra Venkateshaiah Sathisha T Gururaja A Correlation Study on Serum Biomarker and Biochemical Parameters in Acute Heart Failure with Duration of Hospital Stay among Patients with Acute Heart Failure Indian Journal of Medical Biochemistry acute heart failure duration of stay in-patients n‐terminal pro‐b‐type natriuretic peptide prospective observational study |
| title | A Correlation Study on Serum Biomarker and Biochemical Parameters in Acute Heart Failure with Duration of Hospital Stay among Patients with Acute Heart Failure |
| title_full | A Correlation Study on Serum Biomarker and Biochemical Parameters in Acute Heart Failure with Duration of Hospital Stay among Patients with Acute Heart Failure |
| title_fullStr | A Correlation Study on Serum Biomarker and Biochemical Parameters in Acute Heart Failure with Duration of Hospital Stay among Patients with Acute Heart Failure |
| title_full_unstemmed | A Correlation Study on Serum Biomarker and Biochemical Parameters in Acute Heart Failure with Duration of Hospital Stay among Patients with Acute Heart Failure |
| title_short | A Correlation Study on Serum Biomarker and Biochemical Parameters in Acute Heart Failure with Duration of Hospital Stay among Patients with Acute Heart Failure |
| title_sort | correlation study on serum biomarker and biochemical parameters in acute heart failure with duration of hospital stay among patients with acute heart failure |
| topic | acute heart failure duration of stay in-patients n‐terminal pro‐b‐type natriuretic peptide prospective observational study |
| url | https://www.ijmb.in/doi/IJMB/pdf/10.5005/jp-journals-10054-0232 |
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