Differences between mates at the TLR1Lb locus are associated with lower reproductive success in a long-lived seabird
Abstract Genetic diversity can influence fitness components such as survival and reproductive success. Yet the association between genetic diversity and fitness based on neutral loci is sometime very weak and inconsistent, with relationships varying among taxa due to confounding effects of populatio...
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Nature Portfolio
2024-12-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-024-77750-7 |
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| author | Marianne Gousy-Leblanc Thomas Merkling Lila Colston-Nepali Emma Lachance Linklater Kyle H. Elliott Vicki L. Friesen |
| author_facet | Marianne Gousy-Leblanc Thomas Merkling Lila Colston-Nepali Emma Lachance Linklater Kyle H. Elliott Vicki L. Friesen |
| author_sort | Marianne Gousy-Leblanc |
| collection | DOAJ |
| description | Abstract Genetic diversity can influence fitness components such as survival and reproductive success. Yet the association between genetic diversity and fitness based on neutral loci is sometime very weak and inconsistent, with relationships varying among taxa due to confounding effects of population demography and life history. Fitness-diversity relationships are likely to be stronger and more consistent for genes known to influence phenotypic traits, such as immunity-related genes, and may also depend on the genetic differences between breeding partners. We recorded breeding success of individuals and breeding pairs over 20 years to evaluate the relationships between reproductive success and both neutral genetic variation (using 7,830 single nucleotide polymorphisms) and functional variation (four toll-like receptor [TLRs] loci) with reproductive success in thick-billed murres (Uria lomvia). Individual genetic diversity (both neutral and functional) was unrelated to reproductive success, but surprisingly, successful multi-year reproductive success decreased with the genetic difference between breeding partners at TLR1Lb. This result may be due to an advantage of specific alleles at TLR1Lb. This study is one of few addressing both individual genetic variation and genetic similarity between mates at both neutral and functional variation in a long-lived bird. |
| format | Article |
| id | doaj-art-0599e118b8124eaab2219aa819e1ef26 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-0599e118b8124eaab2219aa819e1ef262025-01-05T12:26:45ZengNature PortfolioScientific Reports2045-23222024-12-0114111010.1038/s41598-024-77750-7Differences between mates at the TLR1Lb locus are associated with lower reproductive success in a long-lived seabirdMarianne Gousy-Leblanc0Thomas Merkling1Lila Colston-Nepali2Emma Lachance Linklater3Kyle H. Elliott4Vicki L. Friesen5Department of Natural Resource Sciences, McGill UniversityDepartment of Natural Resource Sciences, McGill UniversityDepartment of Biology, Queen’s UniversityDepartment of Biology, Queen’s UniversityDepartment of Natural Resource Sciences, McGill UniversityDepartment of Biology, Queen’s UniversityAbstract Genetic diversity can influence fitness components such as survival and reproductive success. Yet the association between genetic diversity and fitness based on neutral loci is sometime very weak and inconsistent, with relationships varying among taxa due to confounding effects of population demography and life history. Fitness-diversity relationships are likely to be stronger and more consistent for genes known to influence phenotypic traits, such as immunity-related genes, and may also depend on the genetic differences between breeding partners. We recorded breeding success of individuals and breeding pairs over 20 years to evaluate the relationships between reproductive success and both neutral genetic variation (using 7,830 single nucleotide polymorphisms) and functional variation (four toll-like receptor [TLRs] loci) with reproductive success in thick-billed murres (Uria lomvia). Individual genetic diversity (both neutral and functional) was unrelated to reproductive success, but surprisingly, successful multi-year reproductive success decreased with the genetic difference between breeding partners at TLR1Lb. This result may be due to an advantage of specific alleles at TLR1Lb. This study is one of few addressing both individual genetic variation and genetic similarity between mates at both neutral and functional variation in a long-lived bird.https://doi.org/10.1038/s41598-024-77750-7Brünnich’s guillemotImmunitySingle-nucleotide polymorphismThick-billed murreToll-like receptors |
| spellingShingle | Marianne Gousy-Leblanc Thomas Merkling Lila Colston-Nepali Emma Lachance Linklater Kyle H. Elliott Vicki L. Friesen Differences between mates at the TLR1Lb locus are associated with lower reproductive success in a long-lived seabird Scientific Reports Brünnich’s guillemot Immunity Single-nucleotide polymorphism Thick-billed murre Toll-like receptors |
| title | Differences between mates at the TLR1Lb locus are associated with lower reproductive success in a long-lived seabird |
| title_full | Differences between mates at the TLR1Lb locus are associated with lower reproductive success in a long-lived seabird |
| title_fullStr | Differences between mates at the TLR1Lb locus are associated with lower reproductive success in a long-lived seabird |
| title_full_unstemmed | Differences between mates at the TLR1Lb locus are associated with lower reproductive success in a long-lived seabird |
| title_short | Differences between mates at the TLR1Lb locus are associated with lower reproductive success in a long-lived seabird |
| title_sort | differences between mates at the tlr1lb locus are associated with lower reproductive success in a long lived seabird |
| topic | Brünnich’s guillemot Immunity Single-nucleotide polymorphism Thick-billed murre Toll-like receptors |
| url | https://doi.org/10.1038/s41598-024-77750-7 |
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