Focusing on exosomes to overcome the existing bottlenecks of CAR-T cell therapy

Abstract Since chimeric antigen receptor T (CAR-T) cells were introduced three decades ago, the treatment using these cells has led to outstanding outcomes, and at the moment, CAR-T cell therapy is a well-established mainstay for treating CD19 + malignancies and multiple myeloma. Despite the astonis...

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Bibliographic Details
Main Authors: Si-Heng Zhang, Ling-Long Peng, Yi-Fei Chen, Yan Xu, Vahid Moradi
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Inflammation and Regeneration
Subjects:
Online Access:https://doi.org/10.1186/s41232-024-00358-x
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