A VAMS‐based LC–MS/MS method for precise cenobamate quantification in epilepsy (patients)

A VAMS‐based LC–MS/MS method for precise cenobamate quantification in epilepsy (patients)

Abstract Objective Cenobamate (CNB), a recently approved antiseizure medication by the European Medicines Agency (EMA), serves as an adjunctive therapy for focal‐onset seizures in adult patients unresponsive to at least two other treatments. Administered in polytherapy, CNB can potentially interact...

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Main Authors: Federica Pigliasco, Alessia Cafaro, Sebastiano Barco, Margherita Biondi, Manuela Stella, Francesca Mattioli, Antonella Riva, Ugo deGrazia, Linda Molteni, Elisa Micalizzi, Flavio Villani, Pasquale Striano, Roberto Bandettini, Giuliana Cangemi
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Epilepsia Open
Subjects:
antiseizure medications
cenobamate
drug monitoring
liquid chromatography tandem‐mass spectrometry
volumetric absorptive microsampling
Online Access:https://doi.org/10.1002/epi4.12927
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