A Five-Bundle Intervention to Improve Blood Culture Use in a Tertiary Hospital in Romania
<b>Objectives</b>: The aims of this study were to evaluate the efficacy of a five-bundle intervention and to decrease the number of cases in which only one set of blood cultures is collected prior to starting antimicrobials. <b>Methods</b>: The study group consisted of the tw...
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MDPI AG
2024-11-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/13/11/1040 |
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| author | Alina-Ioana Popa Daniela Tălăpan Gabriel-Adrian Popescu |
| author_facet | Alina-Ioana Popa Daniela Tălăpan Gabriel-Adrian Popescu |
| author_sort | Alina-Ioana Popa |
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| description | <b>Objectives</b>: The aims of this study were to evaluate the efficacy of a five-bundle intervention and to decrease the number of cases in which only one set of blood cultures is collected prior to starting antimicrobials. <b>Methods</b>: The study group consisted of the two hospital wards that have the highest collection rate (120 blood cultures/1000 patient days and 121.4 blood cultures/1000 patient days, respectively), and the control group consisted of the other three adult wards. The collection protocol was changed, and a bundle of five measures was introduced: one-on-one discussions with the nurses, 2% chlorhexidine in 70% alcohol for disinfection, ensuring the use of sterile gloves, sterile wipes, a checklist for the materials needed, and a copy of the collection protocol. The impact of these changes was followed over a 5-month period. <b>Results</b>: Prior to the intervention, the contamination rate was higher in the control group (6.5%) versus the study group (4%), <i>p</i> = 0.00578. The before–after analysis revealed a significantly reduced contamination rate in the control group (4.6% vs. 6.5% <i>p</i> = 0.0099), but it was above the one obtained in the study group (3.1% vs. 4%, <i>p</i> = 0.1635). The number of infectious episodes in which one blood culture set was collected decreased significantly in the study group (77/311 vs. 139/456, <i>p</i> = 0.041). <b>Conclusions</b>: The intervention decreased the contamination rate and the number of infectious episodes in which one blood culture set is collected. |
| format | Article |
| id | doaj-art-05023dd158574000b88c33b5d918d0fe |
| institution | Kabale University |
| issn | 2079-6382 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj-art-05023dd158574000b88c33b5d918d0fe2024-11-26T17:46:28ZengMDPI AGAntibiotics2079-63822024-11-011311104010.3390/antibiotics13111040A Five-Bundle Intervention to Improve Blood Culture Use in a Tertiary Hospital in RomaniaAlina-Ioana Popa0Daniela Tălăpan1Gabriel-Adrian Popescu2Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania<b>Objectives</b>: The aims of this study were to evaluate the efficacy of a five-bundle intervention and to decrease the number of cases in which only one set of blood cultures is collected prior to starting antimicrobials. <b>Methods</b>: The study group consisted of the two hospital wards that have the highest collection rate (120 blood cultures/1000 patient days and 121.4 blood cultures/1000 patient days, respectively), and the control group consisted of the other three adult wards. The collection protocol was changed, and a bundle of five measures was introduced: one-on-one discussions with the nurses, 2% chlorhexidine in 70% alcohol for disinfection, ensuring the use of sterile gloves, sterile wipes, a checklist for the materials needed, and a copy of the collection protocol. The impact of these changes was followed over a 5-month period. <b>Results</b>: Prior to the intervention, the contamination rate was higher in the control group (6.5%) versus the study group (4%), <i>p</i> = 0.00578. The before–after analysis revealed a significantly reduced contamination rate in the control group (4.6% vs. 6.5% <i>p</i> = 0.0099), but it was above the one obtained in the study group (3.1% vs. 4%, <i>p</i> = 0.1635). The number of infectious episodes in which one blood culture set was collected decreased significantly in the study group (77/311 vs. 139/456, <i>p</i> = 0.041). <b>Conclusions</b>: The intervention decreased the contamination rate and the number of infectious episodes in which one blood culture set is collected.https://www.mdpi.com/2079-6382/13/11/1040blood culture collectioncontamination ratebacteremia diagnosis |
| spellingShingle | Alina-Ioana Popa Daniela Tălăpan Gabriel-Adrian Popescu A Five-Bundle Intervention to Improve Blood Culture Use in a Tertiary Hospital in Romania Antibiotics blood culture collection contamination rate bacteremia diagnosis |
| title | A Five-Bundle Intervention to Improve Blood Culture Use in a Tertiary Hospital in Romania |
| title_full | A Five-Bundle Intervention to Improve Blood Culture Use in a Tertiary Hospital in Romania |
| title_fullStr | A Five-Bundle Intervention to Improve Blood Culture Use in a Tertiary Hospital in Romania |
| title_full_unstemmed | A Five-Bundle Intervention to Improve Blood Culture Use in a Tertiary Hospital in Romania |
| title_short | A Five-Bundle Intervention to Improve Blood Culture Use in a Tertiary Hospital in Romania |
| title_sort | five bundle intervention to improve blood culture use in a tertiary hospital in romania |
| topic | blood culture collection contamination rate bacteremia diagnosis |
| url | https://www.mdpi.com/2079-6382/13/11/1040 |
| work_keys_str_mv | AT alinaioanapopa afivebundleinterventiontoimprovebloodcultureuseinatertiaryhospitalinromania AT danielatalapan afivebundleinterventiontoimprovebloodcultureuseinatertiaryhospitalinromania AT gabrieladrianpopescu afivebundleinterventiontoimprovebloodcultureuseinatertiaryhospitalinromania AT alinaioanapopa fivebundleinterventiontoimprovebloodcultureuseinatertiaryhospitalinromania AT danielatalapan fivebundleinterventiontoimprovebloodcultureuseinatertiaryhospitalinromania AT gabrieladrianpopescu fivebundleinterventiontoimprovebloodcultureuseinatertiaryhospitalinromania |