A Custom-Built Piezo-Optical System for Visualization and Characterization of High Intensity Focused Ultrasound

High intensity focused ultrasound (HIFU) is a noninvasive treatment technique to induce thermal or mechanical bioeffects. Characterising the wave field is essential for reliable and reproducible transducer operation in clinical use. This paper presents a schlieren technique to visualise and quantify...

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Main Authors: Brecht Luisa, Steinmeyer Florian, Bonekamp Jörg-Bernd, Partanen Ari, Grüll Holger, Lindemeyer Johannes
Format: Article
Language:English
Published: De Gruyter 2024-12-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2024-2028
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author Brecht Luisa
Steinmeyer Florian
Bonekamp Jörg-Bernd
Partanen Ari
Grüll Holger
Lindemeyer Johannes
author_facet Brecht Luisa
Steinmeyer Florian
Bonekamp Jörg-Bernd
Partanen Ari
Grüll Holger
Lindemeyer Johannes
author_sort Brecht Luisa
collection DOAJ
description High intensity focused ultrasound (HIFU) is a noninvasive treatment technique to induce thermal or mechanical bioeffects. Characterising the wave field is essential for reliable and reproducible transducer operation in clinical use. This paper presents a schlieren technique to visualise and quantify transducer wave fields. The technique is based on the piezo-optical effect of water, i.e. the refractive index variation caused by sound pressure. Our custom-built system equipped with a Raspberry Pi HQ camera can capture schlieren photographs of acoustic fields generated by a clinical HIFU system. Alternatively, a high-speed camera allows analysis of short burst pulses. We investigated the focal zone shape of continuously generated HIFU fields at acoustic powers of 10- 250 W. Images of the focal area at 100 W indicated dimensions comparable to the reported literature values. Notably, as power increases, we observe waveform distortion in the focal zone due to nonlinear propagation of ultrasound. Our findings demonstrate the efficacy of our system in visualizing and characterizing the acoustic fields generated by a clinical HIFU device.
format Article
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institution Kabale University
issn 2364-5504
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publisher De Gruyter
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series Current Directions in Biomedical Engineering
spelling doaj-art-049e503cefb1429fa49ecd9d4ff8608e2025-01-02T05:56:32ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042024-12-0110411511810.1515/cdbme-2024-2028A Custom-Built Piezo-Optical System for Visualization and Characterization of High Intensity Focused UltrasoundBrecht Luisa0Steinmeyer Florian1Bonekamp Jörg-Bernd2Partanen Ari3Grüll Holger4Lindemeyer Johannes5University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Diagnostic and Interventional Radiology, Kerpener Str. 62,Cologne, GermanyFaculty of Applied Mathematics, Physics and Humanities, Technische Hochschule Nürnberg,Nuremberg, GermanySoluxx GmbH,Cologne, GermanyProfound Medical, Mississauga,Ontario, CanadaUniversity of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Diagnostic and Interventional Radiology,Cologne, GermanyUniversity of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Diagnostic and Interventional Radiology,Cologne, GermanyHigh intensity focused ultrasound (HIFU) is a noninvasive treatment technique to induce thermal or mechanical bioeffects. Characterising the wave field is essential for reliable and reproducible transducer operation in clinical use. This paper presents a schlieren technique to visualise and quantify transducer wave fields. The technique is based on the piezo-optical effect of water, i.e. the refractive index variation caused by sound pressure. Our custom-built system equipped with a Raspberry Pi HQ camera can capture schlieren photographs of acoustic fields generated by a clinical HIFU system. Alternatively, a high-speed camera allows analysis of short burst pulses. We investigated the focal zone shape of continuously generated HIFU fields at acoustic powers of 10- 250 W. Images of the focal area at 100 W indicated dimensions comparable to the reported literature values. Notably, as power increases, we observe waveform distortion in the focal zone due to nonlinear propagation of ultrasound. Our findings demonstrate the efficacy of our system in visualizing and characterizing the acoustic fields generated by a clinical HIFU device.https://doi.org/10.1515/cdbme-2024-2028piezo-opticsschlierenshadowgraphyhigh intensity focused ultrasoundhifuboiling histotripsyacoustic field characterization
spellingShingle Brecht Luisa
Steinmeyer Florian
Bonekamp Jörg-Bernd
Partanen Ari
Grüll Holger
Lindemeyer Johannes
A Custom-Built Piezo-Optical System for Visualization and Characterization of High Intensity Focused Ultrasound
Current Directions in Biomedical Engineering
piezo-optics
schlieren
shadowgraphy
high intensity focused ultrasound
hifu
boiling histotripsy
acoustic field characterization
title A Custom-Built Piezo-Optical System for Visualization and Characterization of High Intensity Focused Ultrasound
title_full A Custom-Built Piezo-Optical System for Visualization and Characterization of High Intensity Focused Ultrasound
title_fullStr A Custom-Built Piezo-Optical System for Visualization and Characterization of High Intensity Focused Ultrasound
title_full_unstemmed A Custom-Built Piezo-Optical System for Visualization and Characterization of High Intensity Focused Ultrasound
title_short A Custom-Built Piezo-Optical System for Visualization and Characterization of High Intensity Focused Ultrasound
title_sort custom built piezo optical system for visualization and characterization of high intensity focused ultrasound
topic piezo-optics
schlieren
shadowgraphy
high intensity focused ultrasound
hifu
boiling histotripsy
acoustic field characterization
url https://doi.org/10.1515/cdbme-2024-2028
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