Depression of CaV1.2 activation and expression in mast cells ameliorates allergic inflammation diseases

Depression of CaV1.2 activation and expression in mast cells ameliorates allergic inflammation diseases

Allergic inflammation is closely related to the activation of mast cells (MCs), which is regulated by its intracellular Ca2+ level, but the intake and effects of the intracellular Ca2+ remain unclear. The Ca2+ influx is controlled by members of Ca2+ channels, among which calcium voltage-gated channe...

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Bibliographic Details
Main Authors: Yongjing Zhang, Yingnan Zeng, Haoyun Bai, Wen Zhang, Zhuoyin Xue, Shiling Hu, Shemin Lu, Nan Wang
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Allergy
Asthma
Mast cell
CaV1.2
CaMKII/PKC
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177924002466
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