The fruit fly Drosophila melanogaster as a screening model for antiseizure medications

The fruit fly Drosophila melanogaster as a screening model for antiseizure medications

ObjectiveResistance to antiseizure medications (ASMs) is a major challenge in the treatment of patients with epilepsy. Despite numerous newly marketed ASMs, the proportion of drug-resistant people with epilepsy has not significantly decreased over the years. Therefore, novel and innovative seizure m...

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Bibliographic Details
Main Authors: Florian P. Fischer, Robin A. Karge, Henner Koch, Aaron Voigt, Yvonne G. Weber, Stefan Wolking
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Pharmacology
Subjects:
animal model
antiseizure medications
Drosophila melanogaster
drug screening
epilepsy
seizure model
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1489888/full
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