Clinicopathological characteristics of placental chorioangioma: A clinicopathological study of 30 cases
Objective: The objective is to explore clinicopathological characteristics, diagnosis, differential diagnoses, treatment, and prognoses of placental chorioangioma (PCA). Materials and Methods: The pathological data of 30 cases of PCA were collected; the color Doppler ultrasound, Down’s screening, fe...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-12-01
|
| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_266_23 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841549976117706752 |
|---|---|
| author | Yuanyin Zheng Xiaobin Liu Yingyu Mao Maohua Lin |
| author_facet | Yuanyin Zheng Xiaobin Liu Yingyu Mao Maohua Lin |
| author_sort | Yuanyin Zheng |
| collection | DOAJ |
| description | Objective:
The objective is to explore clinicopathological characteristics, diagnosis, differential diagnoses, treatment, and prognoses of placental chorioangioma (PCA).
Materials and Methods:
The pathological data of 30 cases of PCA were collected; the color Doppler ultrasound, Down’s screening, fetal survival, and pathological characteristics were observed; and the literature was reviewed.
Results:
Of the 30 patients, the ages ranged from 20 to 38 years, with an average of 29.6 years. Pregnancy comorbidity occurred in 14 patients; intrauterine fetal death occurred in 4; the gross appearance of the tumor: a reddish-brown nodule, slightly round, 0.5–8 cm in diameter, can be seen on the cut surface of the placenta Pregnancy comorbidity occurred in 14 patients and intrauterine fetal death in 4. On sectioning the placenta, tumors grossly appeared as reddish-brown nodules, slightly round and ranging in diameter from 0.5 to 8 cm. Microscopically, the tumor has small, densely packed capillaries with fibrous connective tissue in the stroma. There were 10 cases with high risk of Down’s syndrome screening, and the immunophenotype CD34 (+) and Ki-67 proliferation index were less than 10%.
Conclusions:
PCA is rare and may be misdiagnosed as malignant tumor, which may be related to pregnancy comorbidity and high risk of Down’s screening, so improving the understanding of PCA can provide the basis for clinical diagnosis and intervention. PCA is a rare tumor which may be misdiagnosed as a malignancy. It may be related to pregnancy comorbidity and high risk of Down’s screening. Improving the understanding of PCA could provide the basis for clinical diagnosis and intervention. |
| format | Article |
| id | doaj-art-03ec3f6b8a1f49cea208d9bbbfdce1eb |
| institution | Kabale University |
| issn | 0377-4929 0974-5130 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj-art-03ec3f6b8a1f49cea208d9bbbfdce1eb2025-01-10T10:23:18ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302024-12-0167477077410.4103/ijpm.ijpm_266_23Clinicopathological characteristics of placental chorioangioma: A clinicopathological study of 30 casesYuanyin ZhengXiaobin LiuYingyu MaoMaohua LinObjective: The objective is to explore clinicopathological characteristics, diagnosis, differential diagnoses, treatment, and prognoses of placental chorioangioma (PCA). Materials and Methods: The pathological data of 30 cases of PCA were collected; the color Doppler ultrasound, Down’s screening, fetal survival, and pathological characteristics were observed; and the literature was reviewed. Results: Of the 30 patients, the ages ranged from 20 to 38 years, with an average of 29.6 years. Pregnancy comorbidity occurred in 14 patients; intrauterine fetal death occurred in 4; the gross appearance of the tumor: a reddish-brown nodule, slightly round, 0.5–8 cm in diameter, can be seen on the cut surface of the placenta Pregnancy comorbidity occurred in 14 patients and intrauterine fetal death in 4. On sectioning the placenta, tumors grossly appeared as reddish-brown nodules, slightly round and ranging in diameter from 0.5 to 8 cm. Microscopically, the tumor has small, densely packed capillaries with fibrous connective tissue in the stroma. There were 10 cases with high risk of Down’s syndrome screening, and the immunophenotype CD34 (+) and Ki-67 proliferation index were less than 10%. Conclusions: PCA is rare and may be misdiagnosed as malignant tumor, which may be related to pregnancy comorbidity and high risk of Down’s screening, so improving the understanding of PCA can provide the basis for clinical diagnosis and intervention. PCA is a rare tumor which may be misdiagnosed as a malignancy. It may be related to pregnancy comorbidity and high risk of Down’s screening. Improving the understanding of PCA could provide the basis for clinical diagnosis and intervention.https://journals.lww.com/10.4103/ijpm.ijpm_266_23clinicopathological featureimmunohistochemistryplacental chorioangiomapregnancy comorbidities |
| spellingShingle | Yuanyin Zheng Xiaobin Liu Yingyu Mao Maohua Lin Clinicopathological characteristics of placental chorioangioma: A clinicopathological study of 30 cases Indian Journal of Pathology and Microbiology clinicopathological feature immunohistochemistry placental chorioangioma pregnancy comorbidities |
| title | Clinicopathological characteristics of placental chorioangioma: A clinicopathological study of 30 cases |
| title_full | Clinicopathological characteristics of placental chorioangioma: A clinicopathological study of 30 cases |
| title_fullStr | Clinicopathological characteristics of placental chorioangioma: A clinicopathological study of 30 cases |
| title_full_unstemmed | Clinicopathological characteristics of placental chorioangioma: A clinicopathological study of 30 cases |
| title_short | Clinicopathological characteristics of placental chorioangioma: A clinicopathological study of 30 cases |
| title_sort | clinicopathological characteristics of placental chorioangioma a clinicopathological study of 30 cases |
| topic | clinicopathological feature immunohistochemistry placental chorioangioma pregnancy comorbidities |
| url | https://journals.lww.com/10.4103/ijpm.ijpm_266_23 |
| work_keys_str_mv | AT yuanyinzheng clinicopathologicalcharacteristicsofplacentalchorioangiomaaclinicopathologicalstudyof30cases AT xiaobinliu clinicopathologicalcharacteristicsofplacentalchorioangiomaaclinicopathologicalstudyof30cases AT yingyumao clinicopathologicalcharacteristicsofplacentalchorioangiomaaclinicopathologicalstudyof30cases AT maohualin clinicopathologicalcharacteristicsofplacentalchorioangiomaaclinicopathologicalstudyof30cases |