Protocol for a young adult mental health (Uspace) cohort: personalising multidimensional care in young people admitted to hospital
Introduction Currently, the literature on personalised and measurement-based mental healthcare is inadequate with major gaps in the development and evaluation of 21st century service models. Clinical presentations of mental ill health in young people are heterogeneous, and clinical and functional ou...
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| Format: | Article |
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BMJ Publishing Group
2021-01-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/11/1/e038787.full |
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| author | Ian B Hickie Lisa Parker Ashleigh M Tickell Cathrin Rohleder Alexandra Garland Yun Ju Christine Song Joanne Sarah Carpenter Kate Harel Elizabeth Scott |
| author_facet | Ian B Hickie Lisa Parker Ashleigh M Tickell Cathrin Rohleder Alexandra Garland Yun Ju Christine Song Joanne Sarah Carpenter Kate Harel Elizabeth Scott |
| author_sort | Ian B Hickie |
| collection | DOAJ |
| description | Introduction Currently, the literature on personalised and measurement-based mental healthcare is inadequate with major gaps in the development and evaluation of 21st century service models. Clinical presentations of mental ill health in young people are heterogeneous, and clinical and functional outcomes are often suboptimal. Thus, treatments provided in a person-centred and responsive fashion are critical to meet the unique needs of young people and improve individual outcomes. Personalised care also requires concurrent assessment of factors relating to outcomes and underlying neurobiology. This study builds on a completed feasibility study and will be the first to incorporate clinical, cognitive, circadian, metabolic and hormonal profiling with personalised and measurement-based care in a cohort of young people admitted to hospital.Methods and analysis This prospective, transdiagnostic, observational study will be offered to all young people between the ages of 16 and 30 years admitted to the inpatient unit of the participating centre. In total, 400 participants will be recruited. On admission to hospital, young people will undergo clinical and diagnostic assessment, cognitive testing, self-report questionnaires, metabolic and hormonal data collection, and anthropomorphic measurements. Participants will wear an actigraphy watch for at least 1 week during admission to measure circadian patterns and sleep-wake cycles. A feedback session between clinician and participant will occur after clinical and other laboratory assessments to tailor individual treatment plans, explain the ongoing process of measurement-based care, and provide participant and family education. Associations between cognitive impairments, disturbed sleep-wake behaviours, circadian rhythms, clinical symptoms and functional impairments will be evaluated to improve the understanding of parameters affecting clinical outcomes.Ethics and dissemination This study protocol was approved by the Human Research Ethics Committees of the University of Sydney (HREC USYD 2015/867) and St Vincent’s Hospital (HREC SVH 17/045). This study will be published on completion in a peer-reviewed journal. |
| format | Article |
| id | doaj-art-03aaed8f20a3479faa7c032da4c1d868 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-03aaed8f20a3479faa7c032da4c1d8682024-11-18T11:40:08ZengBMJ Publishing GroupBMJ Open2044-60552021-01-0111110.1136/bmjopen-2020-038787Protocol for a young adult mental health (Uspace) cohort: personalising multidimensional care in young people admitted to hospitalIan B Hickie0Lisa Parker1Ashleigh M Tickell2Cathrin Rohleder3Alexandra Garland4Yun Ju Christine Song5Joanne Sarah Carpenter6Kate Harel7Elizabeth Scott8Brain and Mind Centre, Central Clinical School, Faculty of Medicine and Health, The University of Sydney, Camperdown, New South Wales, AustraliaYoung Adult Mental Health Unit, St Vincents Private Hospital, Darlinghurst, New South Wales, AustraliaBrain and Mind Centre, The University of Sydney, Sydney, New South Wales, AustraliaBrain and Mind Centre, The University of Sydney, Sydney, New South Wales, AustraliaBrain and Mind Centre, The University of Sydney, Sydney, New South Wales, AustraliaBrain and Mind Centre, The University of Sydney, Camperdown, New South Wales, AustraliaBrain and Mind Centre, The University of Sydney, Sydney, New South Wales, AustraliaYoung Adult Mental Health Unit, St Vincents Private Hospital, Darlinghurst, New South Wales, AustraliaBrain and Mind Centre, The University of Sydney, Sydney, New South Wales, AustraliaIntroduction Currently, the literature on personalised and measurement-based mental healthcare is inadequate with major gaps in the development and evaluation of 21st century service models. Clinical presentations of mental ill health in young people are heterogeneous, and clinical and functional outcomes are often suboptimal. Thus, treatments provided in a person-centred and responsive fashion are critical to meet the unique needs of young people and improve individual outcomes. Personalised care also requires concurrent assessment of factors relating to outcomes and underlying neurobiology. This study builds on a completed feasibility study and will be the first to incorporate clinical, cognitive, circadian, metabolic and hormonal profiling with personalised and measurement-based care in a cohort of young people admitted to hospital.Methods and analysis This prospective, transdiagnostic, observational study will be offered to all young people between the ages of 16 and 30 years admitted to the inpatient unit of the participating centre. In total, 400 participants will be recruited. On admission to hospital, young people will undergo clinical and diagnostic assessment, cognitive testing, self-report questionnaires, metabolic and hormonal data collection, and anthropomorphic measurements. Participants will wear an actigraphy watch for at least 1 week during admission to measure circadian patterns and sleep-wake cycles. A feedback session between clinician and participant will occur after clinical and other laboratory assessments to tailor individual treatment plans, explain the ongoing process of measurement-based care, and provide participant and family education. Associations between cognitive impairments, disturbed sleep-wake behaviours, circadian rhythms, clinical symptoms and functional impairments will be evaluated to improve the understanding of parameters affecting clinical outcomes.Ethics and dissemination This study protocol was approved by the Human Research Ethics Committees of the University of Sydney (HREC USYD 2015/867) and St Vincent’s Hospital (HREC SVH 17/045). This study will be published on completion in a peer-reviewed journal.https://bmjopen.bmj.com/content/11/1/e038787.full |
| spellingShingle | Ian B Hickie Lisa Parker Ashleigh M Tickell Cathrin Rohleder Alexandra Garland Yun Ju Christine Song Joanne Sarah Carpenter Kate Harel Elizabeth Scott Protocol for a young adult mental health (Uspace) cohort: personalising multidimensional care in young people admitted to hospital BMJ Open |
| title | Protocol for a young adult mental health (Uspace) cohort: personalising multidimensional care in young people admitted to hospital |
| title_full | Protocol for a young adult mental health (Uspace) cohort: personalising multidimensional care in young people admitted to hospital |
| title_fullStr | Protocol for a young adult mental health (Uspace) cohort: personalising multidimensional care in young people admitted to hospital |
| title_full_unstemmed | Protocol for a young adult mental health (Uspace) cohort: personalising multidimensional care in young people admitted to hospital |
| title_short | Protocol for a young adult mental health (Uspace) cohort: personalising multidimensional care in young people admitted to hospital |
| title_sort | protocol for a young adult mental health uspace cohort personalising multidimensional care in young people admitted to hospital |
| url | https://bmjopen.bmj.com/content/11/1/e038787.full |
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