Effect of supplemental dietary phytogenic blends on growth performance, jejunal histomorphometry, and jejunal immunity of broiler chickens
<p>This study evaluated the effects of two phytogenic blends on broiler performance, intestinal histomorphology, CD4<span class="inline-formula"><sup>+</sup></span> (cluster of differentiation) and CD8<span class="inline-formula"><sup>+&l...
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Copernicus Publications
2025-01-01
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| Series: | Archives Animal Breeding |
| Online Access: | https://aab.copernicus.org/articles/68/13/2025/aab-68-13-2025.pdf |
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| author | A. Ceylan P. Saçaklı Ö. Özgenç Çınar M. S. Ramay U. Ahsan U. Ahsan J. A. Harijaona A. G. Bayraktaroğlu F. Manghebati A. Calik |
| author_facet | A. Ceylan P. Saçaklı Ö. Özgenç Çınar M. S. Ramay U. Ahsan U. Ahsan J. A. Harijaona A. G. Bayraktaroğlu F. Manghebati A. Calik |
| author_sort | A. Ceylan |
| collection | DOAJ |
| description | <p>This study evaluated the effects of two phytogenic blends on broiler performance, intestinal histomorphology, CD4<span class="inline-formula"><sup>+</sup></span> (cluster of differentiation) and CD8<span class="inline-formula"><sup>+</sup></span> T-cell numbers, and mRNA abundances of several cytokines in broilers. For this purpose, a total of 300 Ross 308 male broiler chicks that were 1 d old were randomly allocated to five experimental groups. The control group was fed a basal diet without any additives, and there were two phytogenic supplement groups (blend A, mainly comprising extracts of <i>Thymus</i> <i>vulgaris</i> and <i>Filipendula</i> <i>ulmaria</i>, and blend B, consisting of <i>Ginkgo</i>
<i>biloba</i> and <i>Silybum</i> <i>marianum</i>) with two dosage regimens each (100 and 200 mg kg<span class="inline-formula"><sup>−1</sup></span> (denoted A<span class="inline-formula"><sub>100</sub></span> and A<span class="inline-formula"><sub>200</sub></span>) and 100 and 300 mg kg<span class="inline-formula"><sup>−1</sup></span> (B<span class="inline-formula"><sub>100</sub></span> and B<span class="inline-formula"><sub>300</sub></span>) of the diet, respectively). Over the total growing period, body weight gain and feed intake were unchanged among the groups, although phytogenic blend B showed a dose-dependent improvement in feed conversion ratio. Both phytogenic blends did not affect carcass characteristics. Jejunal morphology (villus height, crypt depth, and their ratio) was modified depending on both the composition and the dosage levels of the selected phytogenics. Also, both phytogenic blends linearly increased the CD4<span class="inline-formula"><sup>+</sup></span> and CD8<span class="inline-formula"><sup>+</sup></span> T-cell numbers in the jejunum. Moreover, no major treatment effects were observed on mRNA abundances of cytokines (IL-1<span class="inline-formula"><i>β</i></span>, IL-6, and TNF<span class="inline-formula"><i>α</i></span>). However, across the two phytogenic additives employed, a positive linear dose response in IL-1<span class="inline-formula"><i>β</i></span> abundance was noted on day 21 in broilers fed phytogenic blend B. Overall, dietary phytogenic blend B improved the intestinal health and growth performance of chickens compared to blend A. Further studies are suggested to elucidate the effects of the tested phytogenic blends on gut microbiome and on oxidative stress in broiler chickens.</p> |
| format | Article |
| id | doaj-art-03a3a316eb9c4c718f173e753dd02d01 |
| institution | Kabale University |
| issn | 0003-9438 2363-9822 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Copernicus Publications |
| record_format | Article |
| series | Archives Animal Breeding |
| spelling | doaj-art-03a3a316eb9c4c718f173e753dd02d012025-01-06T10:55:08ZengCopernicus PublicationsArchives Animal Breeding0003-94382363-98222025-01-0168132610.5194/aab-68-13-2025Effect of supplemental dietary phytogenic blends on growth performance, jejunal histomorphometry, and jejunal immunity of broiler chickensA. Ceylan0P. Saçaklı1Ö. Özgenç Çınar2M. S. Ramay3U. Ahsan4U. Ahsan5J. A. Harijaona6A. G. Bayraktaroğlu7F. Manghebati8A. Calik9Department of Histology and Embryology, Faculty of Veterinary Medicine, Ankara University, Ankara, 06110, TürkiyeDepartment of Animal Nutrition and Nutritional Diseases, Faculty of Veterinary Medicine, Ankara University, Ankara, 06110, TürkiyeDepartment of Histology and Embryology, Faculty of Veterinary Medicine, Ankara University, Ankara, 06110, TürkiyeDepartment of Animal Nutrition and Nutritional Diseases, Faculty of Veterinary Medicine, Ankara University, Ankara, 06110, TürkiyeDepartment of Plant and Animal Production, Burdur Vocational School of Food, Agriculture and Livestock, Burdur Mehmet Akif Ersoy University, Burdur, 15030, TürkiyeCenter for Agriculture, Livestock and Food Research, Burdur Mehmet Akif Ersoy University, Burdur, 15030, TürkiyeDepartment of Animal Nutrition and Nutritional Diseases, Faculty of Veterinary Medicine, Ankara University, Ankara, 06110, TürkiyeDepartment of Histology and Embryology, Faculty of Veterinary Medicine, Ankara University, Ankara, 06110, TürkiyeManghebati S. A., Zone de la Basse Haye, Châteaubourg, 35220, FranceDepartment of Animal Nutrition and Nutritional Diseases, Faculty of Veterinary Medicine, Ankara University, Ankara, 06110, Türkiye<p>This study evaluated the effects of two phytogenic blends on broiler performance, intestinal histomorphology, CD4<span class="inline-formula"><sup>+</sup></span> (cluster of differentiation) and CD8<span class="inline-formula"><sup>+</sup></span> T-cell numbers, and mRNA abundances of several cytokines in broilers. For this purpose, a total of 300 Ross 308 male broiler chicks that were 1 d old were randomly allocated to five experimental groups. The control group was fed a basal diet without any additives, and there were two phytogenic supplement groups (blend A, mainly comprising extracts of <i>Thymus</i> <i>vulgaris</i> and <i>Filipendula</i> <i>ulmaria</i>, and blend B, consisting of <i>Ginkgo</i> <i>biloba</i> and <i>Silybum</i> <i>marianum</i>) with two dosage regimens each (100 and 200 mg kg<span class="inline-formula"><sup>−1</sup></span> (denoted A<span class="inline-formula"><sub>100</sub></span> and A<span class="inline-formula"><sub>200</sub></span>) and 100 and 300 mg kg<span class="inline-formula"><sup>−1</sup></span> (B<span class="inline-formula"><sub>100</sub></span> and B<span class="inline-formula"><sub>300</sub></span>) of the diet, respectively). Over the total growing period, body weight gain and feed intake were unchanged among the groups, although phytogenic blend B showed a dose-dependent improvement in feed conversion ratio. Both phytogenic blends did not affect carcass characteristics. Jejunal morphology (villus height, crypt depth, and their ratio) was modified depending on both the composition and the dosage levels of the selected phytogenics. Also, both phytogenic blends linearly increased the CD4<span class="inline-formula"><sup>+</sup></span> and CD8<span class="inline-formula"><sup>+</sup></span> T-cell numbers in the jejunum. Moreover, no major treatment effects were observed on mRNA abundances of cytokines (IL-1<span class="inline-formula"><i>β</i></span>, IL-6, and TNF<span class="inline-formula"><i>α</i></span>). However, across the two phytogenic additives employed, a positive linear dose response in IL-1<span class="inline-formula"><i>β</i></span> abundance was noted on day 21 in broilers fed phytogenic blend B. Overall, dietary phytogenic blend B improved the intestinal health and growth performance of chickens compared to blend A. Further studies are suggested to elucidate the effects of the tested phytogenic blends on gut microbiome and on oxidative stress in broiler chickens.</p>https://aab.copernicus.org/articles/68/13/2025/aab-68-13-2025.pdf |
| spellingShingle | A. Ceylan P. Saçaklı Ö. Özgenç Çınar M. S. Ramay U. Ahsan U. Ahsan J. A. Harijaona A. G. Bayraktaroğlu F. Manghebati A. Calik Effect of supplemental dietary phytogenic blends on growth performance, jejunal histomorphometry, and jejunal immunity of broiler chickens Archives Animal Breeding |
| title | Effect of supplemental dietary phytogenic blends on growth performance, jejunal histomorphometry, and jejunal immunity of broiler chickens |
| title_full | Effect of supplemental dietary phytogenic blends on growth performance, jejunal histomorphometry, and jejunal immunity of broiler chickens |
| title_fullStr | Effect of supplemental dietary phytogenic blends on growth performance, jejunal histomorphometry, and jejunal immunity of broiler chickens |
| title_full_unstemmed | Effect of supplemental dietary phytogenic blends on growth performance, jejunal histomorphometry, and jejunal immunity of broiler chickens |
| title_short | Effect of supplemental dietary phytogenic blends on growth performance, jejunal histomorphometry, and jejunal immunity of broiler chickens |
| title_sort | effect of supplemental dietary phytogenic blends on growth performance jejunal histomorphometry and jejunal immunity of broiler chickens |
| url | https://aab.copernicus.org/articles/68/13/2025/aab-68-13-2025.pdf |
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