Clinical analysis of 126 cases of stillbirth in high-altitude areas
Abstract Objective This study aims to analyze the clinical characteristics of stillbirths in high-altitude areas, strengthen monitoring of high-risk pregnant women, improve maternal health care levels, and reduce perinatal mortality rates. Methods A retrospective collection of 126 cases of stillbirt...
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BMC
2025-05-01
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| Series: | BMC Pregnancy and Childbirth |
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| Online Access: | https://doi.org/10.1186/s12884-025-07670-5 |
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| author | Yunbo Huang Weijie Fan Xinxin Xie Donghua Yao |
| author_facet | Yunbo Huang Weijie Fan Xinxin Xie Donghua Yao |
| author_sort | Yunbo Huang |
| collection | DOAJ |
| description | Abstract Objective This study aims to analyze the clinical characteristics of stillbirths in high-altitude areas, strengthen monitoring of high-risk pregnant women, improve maternal health care levels, and reduce perinatal mortality rates. Methods A retrospective collection of 126 cases of stillbirth in Nyingchi People’s Hospital from 2015 to 2021 was divided into an pre-stage group (2015–2019,87 cases) and a post-stage group (2020–2021,39 cases). The incidence of stillbirth and clinical characteristics were compared between the two groups. The cases were classified into maternal factors, fetal factors, placenta/membrane/umbilical cord factors, and unknown causes, and the clinical characteristics and possible etiologies of different gestational ages and antenatal examination situations were analyzed. Result The overall incidence of stillbirth in the high-altitude area of this study was 2.36%, with2.07% in the pre-stage group and 3.43% in the post-stage group. There were significant differences between the two groups in gestational age and antenatal examination situation (P = 0.003 and 0.008). The main causes of stillbirth were maternal factors (45.28%), followed by placenta/membrane and umbilical cord factors (28.30%), unknown causes (17.61%), and fetal factors (8.81%). The main causes of stillbirth include hypertensive disorder complicating pregnancy, premature rupture of membranes, severe anemia, and fetal malformatiohypertensive disorder complicating pregnancyns. Conclusion This study provides new insights into the prevention and management of stillbirths in high-altitude areas, particularly in terms of maternal factors such as gestational hypertension and severe anemia, by analyzing the clinical characteristics and influencing factors of 126 cases of stillbirths in high-altitude areas. Therefore, this study suggests strengthening prenatal and antenatal health care management to reduce the risk of stillbirth, improve pregnancy outcomes, and promote maternal and child health. |
| format | Article |
| id | doaj-art-037f78a7b1ff470fa74d5c49f4b5303a |
| institution | Kabale University |
| issn | 1471-2393 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pregnancy and Childbirth |
| spelling | doaj-art-037f78a7b1ff470fa74d5c49f4b5303a2025-08-20T03:53:57ZengBMCBMC Pregnancy and Childbirth1471-23932025-05-012511910.1186/s12884-025-07670-5Clinical analysis of 126 cases of stillbirth in high-altitude areasYunbo Huang0Weijie Fan1Xinxin Xie2Donghua Yao3Department of Obstetrics, The Third Affiliated Hospital of Guangzhou Medical UniversityDepartment of Obstetrics and Gynaecology, Linzhi People’s HospitalDepartment of Obstetrics and Gynaecology, Linzhi People’s HospitalDepartment of Obstetrics and Gynaecology, Linzhi People’s HospitalAbstract Objective This study aims to analyze the clinical characteristics of stillbirths in high-altitude areas, strengthen monitoring of high-risk pregnant women, improve maternal health care levels, and reduce perinatal mortality rates. Methods A retrospective collection of 126 cases of stillbirth in Nyingchi People’s Hospital from 2015 to 2021 was divided into an pre-stage group (2015–2019,87 cases) and a post-stage group (2020–2021,39 cases). The incidence of stillbirth and clinical characteristics were compared between the two groups. The cases were classified into maternal factors, fetal factors, placenta/membrane/umbilical cord factors, and unknown causes, and the clinical characteristics and possible etiologies of different gestational ages and antenatal examination situations were analyzed. Result The overall incidence of stillbirth in the high-altitude area of this study was 2.36%, with2.07% in the pre-stage group and 3.43% in the post-stage group. There were significant differences between the two groups in gestational age and antenatal examination situation (P = 0.003 and 0.008). The main causes of stillbirth were maternal factors (45.28%), followed by placenta/membrane and umbilical cord factors (28.30%), unknown causes (17.61%), and fetal factors (8.81%). The main causes of stillbirth include hypertensive disorder complicating pregnancy, premature rupture of membranes, severe anemia, and fetal malformatiohypertensive disorder complicating pregnancyns. Conclusion This study provides new insights into the prevention and management of stillbirths in high-altitude areas, particularly in terms of maternal factors such as gestational hypertension and severe anemia, by analyzing the clinical characteristics and influencing factors of 126 cases of stillbirths in high-altitude areas. Therefore, this study suggests strengthening prenatal and antenatal health care management to reduce the risk of stillbirth, improve pregnancy outcomes, and promote maternal and child health.https://doi.org/10.1186/s12884-025-07670-5High-altitude areaStillbirthGestational ageMaternal factorsObstetric care |
| spellingShingle | Yunbo Huang Weijie Fan Xinxin Xie Donghua Yao Clinical analysis of 126 cases of stillbirth in high-altitude areas BMC Pregnancy and Childbirth High-altitude area Stillbirth Gestational age Maternal factors Obstetric care |
| title | Clinical analysis of 126 cases of stillbirth in high-altitude areas |
| title_full | Clinical analysis of 126 cases of stillbirth in high-altitude areas |
| title_fullStr | Clinical analysis of 126 cases of stillbirth in high-altitude areas |
| title_full_unstemmed | Clinical analysis of 126 cases of stillbirth in high-altitude areas |
| title_short | Clinical analysis of 126 cases of stillbirth in high-altitude areas |
| title_sort | clinical analysis of 126 cases of stillbirth in high altitude areas |
| topic | High-altitude area Stillbirth Gestational age Maternal factors Obstetric care |
| url | https://doi.org/10.1186/s12884-025-07670-5 |
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