Mycotic aneurysm due to Magnusiomyces capitatus complicating a second liver transplant in a colonized patient
This report presents an extremely rare case of a fungal mycotic aneurysm due to Magnusiomyces capitatus in a 51-year-old woman who is immunocompromised. The diagnosis was based on multiple computed tomography scans and the identification of the pathogen via sequencing of the internal transcribed spa...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-02-01
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| Series: | International Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971224004454 |
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| Summary: | This report presents an extremely rare case of a fungal mycotic aneurysm due to Magnusiomyces capitatus in a 51-year-old woman who is immunocompromised. The diagnosis was based on multiple computed tomography scans and the identification of the pathogen via sequencing of the internal transcribed spacer region. Long-term treatment with caspofungin for previous candidemia likely promoted the dissemination of this intrinsically echinocandin-resistant fungus from colonization sites in the lungs and rectal area. Long-term suppressive antifungal therapy with voriconazole and subsequently with posaconazole, combined with multiple surgical procedures, led to an improvement in the patient's condition. This case highlights the importance of considering a patient's comprehensive microbiological history and reassessing antimicrobial therapy in cases of nonimprovement or relapse. |
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| ISSN: | 1201-9712 |