Turn TRAIL Into Better Anticancer Therapeutic Through TRAIL Fusion Proteins

Turn TRAIL Into Better Anticancer Therapeutic Through TRAIL Fusion Proteins

ABSTRACT Background TNF‐related apoptosis‐inducing ligand (TRAIL) belongs to the tumor necrosis factor superfamily. TRAIL selectively induces apoptosis in tumor cells while sparing normal cells, which makes it an attractive candidate for cancer therapy. Recombinant soluble TRAIL and agonistic antibo...

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Bibliographic Details
Main Authors: Yan Wang, Xin Qian, Yubo Wang, Caiyuan Yu, Li Feng, Xiaoyan Zheng, Yaya Wang, Qiuhong Gong
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Cancer Medicine
Subjects:
apoptosis
cancer
fusion protein
resistance
TRAIL
Online Access:https://doi.org/10.1002/cam4.70517
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