Current Endoscopic and Surgical Management of Pancreatic Cystic Lesions: A Comprehensive Review

Pancreatic cystic lesions (PCLs) are frequent incidental findings with an increasing prevalence with age. For these significant lesions, accurate characterization of cyst type and prediction of the risk of malignant progression are crucial for specific management, such as deciding to monitor a lesio...

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Main Authors: Kunzah A. Syed, Elham Afghani, Kelly J. Lafaro
Format: Article
Language:English
Published: AVES 2025-01-01
Series:The Turkish Journal of Gastroenterology
Online Access:https://www.turkjgastroenterol.org/en/current-endoscopic-and-surgical-management-of-pancreatic-cystic-lesions-a-comprehensive-review-137288
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author Kunzah A. Syed
Elham Afghani
Kelly J. Lafaro
author_facet Kunzah A. Syed
Elham Afghani
Kelly J. Lafaro
author_sort Kunzah A. Syed
collection DOAJ
description Pancreatic cystic lesions (PCLs) are frequent incidental findings with an increasing prevalence with age. For these significant lesions, accurate characterization of cyst type and prediction of the risk of malignant progression are crucial for specific management, such as deciding to monitor a lesion or pursue surgical intervention. Fortunately, endoscopy-based diagnostic and therapeutic techniques like endoscopic ultrasound with fine needle aspiration, confocal endomicroscopy, through-the-needle biopsy, contrast-enhanced endoscopic ultrasound, ablation, and pancreatoscopy have enabled increasingly accurate diagnoses of PCLs. Surgical management should be considered in certain cases. This narrative review’s objective is to appraise and synthesize the salient literature on the endoscopic and surgical management of PCLs to aid clinician decision-making. We analyze the current data and explore the benefits, challenges, and future prospects of endoscopy and surgery for pancreatic cysts.
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spelling doaj-art-0358e210cc674d3e996e7a0d537589ab2025-01-09T14:50:01ZengAVESThe Turkish Journal of Gastroenterology2148-56072025-01-0136161410.5152/tjg.2024.24124Current Endoscopic and Surgical Management of Pancreatic Cystic Lesions: A Comprehensive ReviewKunzah A. Syed 0Elham Afghani1Kelly J. Lafaro2Division of Gastroenterology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA ; Department of Medicine, Pancreatitis Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, USADivision of Gastroenterology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA ; Department of Medicine, Pancreatitis Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, USADivision of Hepato-Pancreato-Biliary Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USAPancreatic cystic lesions (PCLs) are frequent incidental findings with an increasing prevalence with age. For these significant lesions, accurate characterization of cyst type and prediction of the risk of malignant progression are crucial for specific management, such as deciding to monitor a lesion or pursue surgical intervention. Fortunately, endoscopy-based diagnostic and therapeutic techniques like endoscopic ultrasound with fine needle aspiration, confocal endomicroscopy, through-the-needle biopsy, contrast-enhanced endoscopic ultrasound, ablation, and pancreatoscopy have enabled increasingly accurate diagnoses of PCLs. Surgical management should be considered in certain cases. This narrative review’s objective is to appraise and synthesize the salient literature on the endoscopic and surgical management of PCLs to aid clinician decision-making. We analyze the current data and explore the benefits, challenges, and future prospects of endoscopy and surgery for pancreatic cysts.https://www.turkjgastroenterol.org/en/current-endoscopic-and-surgical-management-of-pancreatic-cystic-lesions-a-comprehensive-review-137288
spellingShingle Kunzah A. Syed
Elham Afghani
Kelly J. Lafaro
Current Endoscopic and Surgical Management of Pancreatic Cystic Lesions: A Comprehensive Review
The Turkish Journal of Gastroenterology
title Current Endoscopic and Surgical Management of Pancreatic Cystic Lesions: A Comprehensive Review
title_full Current Endoscopic and Surgical Management of Pancreatic Cystic Lesions: A Comprehensive Review
title_fullStr Current Endoscopic and Surgical Management of Pancreatic Cystic Lesions: A Comprehensive Review
title_full_unstemmed Current Endoscopic and Surgical Management of Pancreatic Cystic Lesions: A Comprehensive Review
title_short Current Endoscopic and Surgical Management of Pancreatic Cystic Lesions: A Comprehensive Review
title_sort current endoscopic and surgical management of pancreatic cystic lesions a comprehensive review
url https://www.turkjgastroenterol.org/en/current-endoscopic-and-surgical-management-of-pancreatic-cystic-lesions-a-comprehensive-review-137288
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