Extraction and Characterization of Bioactive Fish By-Product Collagen as Promising for Potential Wound Healing Agent in Pharmaceutical Applications: Current Trend and Future Perspective
Collagen is a structural protein naturally found in mammals. Vertebrates and other connective tissues comprise about 30% of an animal’s overall protein. Collagen is used in a variety of applications including cosmetics, biomedical, biomaterials, food, and pharmaceuticals. The use of marine-based col...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | International Journal of Food Science |
| Online Access: | http://dx.doi.org/10.1155/2022/9437878 |
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| _version_ | 1849309232726278144 |
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| author | Siti Nur Hazwani Oslan Cheng Xue Li Rossita Shapawi Ruzaidi Azli Mohd Mokhtar Wan Norhana Md. Noordin Nurul Huda |
| author_facet | Siti Nur Hazwani Oslan Cheng Xue Li Rossita Shapawi Ruzaidi Azli Mohd Mokhtar Wan Norhana Md. Noordin Nurul Huda |
| author_sort | Siti Nur Hazwani Oslan |
| collection | DOAJ |
| description | Collagen is a structural protein naturally found in mammals. Vertebrates and other connective tissues comprise about 30% of an animal’s overall protein. Collagen is used in a variety of applications including cosmetics, biomedical, biomaterials, food, and pharmaceuticals. The use of marine-based collagen as a substitute source is rapidly increasing due to its unique properties, which include the absence of religious restrictions, a low molecular weight, no risk of disease transmission, biocompatibility, and ease of absorption by the body system. This review discusses recent research on collagen extraction from marine-based raw material, specifically fish by-products. Furthermore, pretreatment on various sources of fish materials, followed by extraction methods, was described. The extraction procedures for acid soluble collagen (ASC) and pepsin soluble collagen (PSC) for fish collagen isolation are specifically discussed and compared. As a result, the efficacy of collagen yield was also demonstrated. The recent trend of extracting fish collagen from marine biomaterials has been summarized, with the potential to be exploited as a wound healing agent in pharmaceutical applications. Furthermore, background information on collagen and characterization techniques primarily related to the composition, properties, and structure of fish collagen are discussed. |
| format | Article |
| id | doaj-art-032e46c363d243518f4a28a8acd8a4ce |
| institution | Kabale University |
| issn | 2314-5765 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Food Science |
| spelling | doaj-art-032e46c363d243518f4a28a8acd8a4ce2025-08-20T03:54:14ZengWileyInternational Journal of Food Science2314-57652022-01-01202210.1155/2022/9437878Extraction and Characterization of Bioactive Fish By-Product Collagen as Promising for Potential Wound Healing Agent in Pharmaceutical Applications: Current Trend and Future PerspectiveSiti Nur Hazwani Oslan0Cheng Xue Li1Rossita Shapawi2Ruzaidi Azli Mohd Mokhtar3Wan Norhana Md. Noordin4Nurul Huda5Faculty of Food Science and NutritionFaculty of Food Science and NutritionBorneo Marine Research InstituteBiotechnology Research InstituteFisheries Research InstituteFaculty of Food Science and NutritionCollagen is a structural protein naturally found in mammals. Vertebrates and other connective tissues comprise about 30% of an animal’s overall protein. Collagen is used in a variety of applications including cosmetics, biomedical, biomaterials, food, and pharmaceuticals. The use of marine-based collagen as a substitute source is rapidly increasing due to its unique properties, which include the absence of religious restrictions, a low molecular weight, no risk of disease transmission, biocompatibility, and ease of absorption by the body system. This review discusses recent research on collagen extraction from marine-based raw material, specifically fish by-products. Furthermore, pretreatment on various sources of fish materials, followed by extraction methods, was described. The extraction procedures for acid soluble collagen (ASC) and pepsin soluble collagen (PSC) for fish collagen isolation are specifically discussed and compared. As a result, the efficacy of collagen yield was also demonstrated. The recent trend of extracting fish collagen from marine biomaterials has been summarized, with the potential to be exploited as a wound healing agent in pharmaceutical applications. Furthermore, background information on collagen and characterization techniques primarily related to the composition, properties, and structure of fish collagen are discussed.http://dx.doi.org/10.1155/2022/9437878 |
| spellingShingle | Siti Nur Hazwani Oslan Cheng Xue Li Rossita Shapawi Ruzaidi Azli Mohd Mokhtar Wan Norhana Md. Noordin Nurul Huda Extraction and Characterization of Bioactive Fish By-Product Collagen as Promising for Potential Wound Healing Agent in Pharmaceutical Applications: Current Trend and Future Perspective International Journal of Food Science |
| title | Extraction and Characterization of Bioactive Fish By-Product Collagen as Promising for Potential Wound Healing Agent in Pharmaceutical Applications: Current Trend and Future Perspective |
| title_full | Extraction and Characterization of Bioactive Fish By-Product Collagen as Promising for Potential Wound Healing Agent in Pharmaceutical Applications: Current Trend and Future Perspective |
| title_fullStr | Extraction and Characterization of Bioactive Fish By-Product Collagen as Promising for Potential Wound Healing Agent in Pharmaceutical Applications: Current Trend and Future Perspective |
| title_full_unstemmed | Extraction and Characterization of Bioactive Fish By-Product Collagen as Promising for Potential Wound Healing Agent in Pharmaceutical Applications: Current Trend and Future Perspective |
| title_short | Extraction and Characterization of Bioactive Fish By-Product Collagen as Promising for Potential Wound Healing Agent in Pharmaceutical Applications: Current Trend and Future Perspective |
| title_sort | extraction and characterization of bioactive fish by product collagen as promising for potential wound healing agent in pharmaceutical applications current trend and future perspective |
| url | http://dx.doi.org/10.1155/2022/9437878 |
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