“Bacillus cereus” Outbreak in a Tertiary Hospital in Manila, Philippines
AIM: This investigation aimed to describe Bacillus cereus (B. cereus) outbreak. BACKGROUND: B. cereus is often considered a contaminant in blood cultures. However, B. cereus can cause severe infections among hospitalized immunocompromised patients. A series of B. cereus infections were documented be...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | Journal of Global Antimicrobial Resistance |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213716524003941 |
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| author | Yvette Marie Marcellana Eder Arpon Janice Campos Caoili |
| author_facet | Yvette Marie Marcellana Eder Arpon Janice Campos Caoili |
| author_sort | Yvette Marie Marcellana Eder Arpon |
| collection | DOAJ |
| description | AIM: This investigation aimed to describe Bacillus cereus (B. cereus) outbreak. BACKGROUND: B. cereus is often considered a contaminant in blood cultures. However, B. cereus can cause severe infections among hospitalized immunocompromised patients. A series of B. cereus infections were documented between February 9, 2023 until August 1, 2024 at Makati Medical Center. METHODS: An outbreak investigation was conducted on March 20, 2024. Patient profiles were reviewed to determine possible risk factors to guide further outbreak investigation interventions. RESULTS: There were a total of 12 cases. The median age of cases was 66.5 years old. Majority (9 or 75%) were females, 7 or 58% were on chronic hemodialysis. 11 or 92% had a central line. B. cereus was isolated from the blood in 8 or 66% of the cases all of whom had a central line. 7 or 58% underwent a surgical procedure during admission. Among 8 (67%) of cases, B. cereus was isolated from blood or other specimens after 48 hours from admission. Only 4 (33%) had gastrointestinal symptoms. Two cases expired. Central line associated bloodstream infection prevention measures were reinforced in patient care areas. Sampling of dialysate fluid in the dialysis unit did not reveal the organism. CONCLUSIONS: Patients with a central line and undergoing hemodialysis comprise majority of cases with B. cereus infection. Breach in infection control measures can predispose patients infections. Early identification and outbreak investigation can determine common patient profiles that guide effective interventions. |
| format | Article |
| id | doaj-art-02f206a8c25f4cc6b096400413a88cbc |
| institution | Kabale University |
| issn | 2213-7165 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Global Antimicrobial Resistance |
| spelling | doaj-art-02f206a8c25f4cc6b096400413a88cbc2024-12-27T04:08:49ZengElsevierJournal of Global Antimicrobial Resistance2213-71652024-12-01396768“Bacillus cereus” Outbreak in a Tertiary Hospital in Manila, PhilippinesYvette Marie Marcellana Eder Arpon0Janice Campos Caoili1Makati Medical Center, Makati City, PhilippinesMakati Medical Center, Makati City, PhilippinesAIM: This investigation aimed to describe Bacillus cereus (B. cereus) outbreak. BACKGROUND: B. cereus is often considered a contaminant in blood cultures. However, B. cereus can cause severe infections among hospitalized immunocompromised patients. A series of B. cereus infections were documented between February 9, 2023 until August 1, 2024 at Makati Medical Center. METHODS: An outbreak investigation was conducted on March 20, 2024. Patient profiles were reviewed to determine possible risk factors to guide further outbreak investigation interventions. RESULTS: There were a total of 12 cases. The median age of cases was 66.5 years old. Majority (9 or 75%) were females, 7 or 58% were on chronic hemodialysis. 11 or 92% had a central line. B. cereus was isolated from the blood in 8 or 66% of the cases all of whom had a central line. 7 or 58% underwent a surgical procedure during admission. Among 8 (67%) of cases, B. cereus was isolated from blood or other specimens after 48 hours from admission. Only 4 (33%) had gastrointestinal symptoms. Two cases expired. Central line associated bloodstream infection prevention measures were reinforced in patient care areas. Sampling of dialysate fluid in the dialysis unit did not reveal the organism. CONCLUSIONS: Patients with a central line and undergoing hemodialysis comprise majority of cases with B. cereus infection. Breach in infection control measures can predispose patients infections. Early identification and outbreak investigation can determine common patient profiles that guide effective interventions.http://www.sciencedirect.com/science/article/pii/S2213716524003941Bacillus cereusoutbreak investigationcentral line associated bloodstream infectiondialysishospital acquired infection |
| spellingShingle | Yvette Marie Marcellana Eder Arpon Janice Campos Caoili “Bacillus cereus” Outbreak in a Tertiary Hospital in Manila, Philippines Journal of Global Antimicrobial Resistance Bacillus cereus outbreak investigation central line associated bloodstream infection dialysis hospital acquired infection |
| title | “Bacillus cereus” Outbreak in a Tertiary Hospital in Manila, Philippines |
| title_full | “Bacillus cereus” Outbreak in a Tertiary Hospital in Manila, Philippines |
| title_fullStr | “Bacillus cereus” Outbreak in a Tertiary Hospital in Manila, Philippines |
| title_full_unstemmed | “Bacillus cereus” Outbreak in a Tertiary Hospital in Manila, Philippines |
| title_short | “Bacillus cereus” Outbreak in a Tertiary Hospital in Manila, Philippines |
| title_sort | bacillus cereus outbreak in a tertiary hospital in manila philippines |
| topic | Bacillus cereus outbreak investigation central line associated bloodstream infection dialysis hospital acquired infection |
| url | http://www.sciencedirect.com/science/article/pii/S2213716524003941 |
| work_keys_str_mv | AT yvettemariemarcellanaederarpon bacilluscereusoutbreakinatertiaryhospitalinmanilaphilippines AT janicecamposcaoili bacilluscereusoutbreakinatertiaryhospitalinmanilaphilippines |