Delivery of N-heterocyclic drugs, acids, phenols, and thiols via Tailor−made Self−immolative linkers
Heterocyclic drugs display diverse pharmacological activities and metabolic stability. However, their poor solubility and pharmacokinetic properties often compromise bioavailability and clinical outcomes. Nevertheless, the prodrug approach provides a viable strategy to overcome unwanted attributes o...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-12-01
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| Series: | European Journal of Medicinal Chemistry Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772417424000888 |
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