Enhancing ovarian cancer treatment: Synergistic effects of methotrexate (Methotrexate)- and quercetin-loaded chitosan nanoparticles

Enhancing ovarian cancer treatment: Synergistic effects of methotrexate (Methotrexate)- and quercetin-loaded chitosan nanoparticles

Ovarian cancer, a leading cause of cancer-related deaths in women, is often diagnosed at advanced stages and exhibits treatment resistance. This study investigates chitosan-based nanoparticles (Cs NPs) as a drug delivery system to enhance the efficacy of methotrexate (MTX) and quercetin (Que) in ova...

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Bibliographic Details
Main Authors: Hamed Dadashi, Amir Reza Nazemiyeh, Alireza Karimian-Shaddel, Milad mashinchian, Aria Mohabbat, Shahrbano Karamnejad Faragheh, Somayeh Vandghanooni, Morteza Eskandani
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Carbohydrate Polymer Technologies and Applications
Subjects:
Ovarian neoplasms
Methotrexate (Methotrexate)
Quercetin
Chitosan nanoparticles
Drug delivery systems
Antineoplastic agents
Online Access:http://www.sciencedirect.com/science/article/pii/S2666893924001993
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