Personalized statin therapy: Targeting metabolic processes to modulate the therapeutic and adverse effects of statins

Personalized statin therapy: Targeting metabolic processes to modulate the therapeutic and adverse effects of statins

Statins are widely used for treating lipid disorders and cardiovascular diseases. However, the therapeutic efficiency and adverse effects of statins vary among different patients, which numerous clinical and epidemiological studies have attributed to genetic polymorphisms in statin-metabolizing enzy...

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Bibliographic Details
Main Authors:	Zhuangqi Shi, Shuxin Han
Format:	Article
Language:	English
Published:	Elsevier 2025-01-01
Series:	Heliyon
Subjects:	Statin Adverse effects Drug metabolism Hepatic uptake Drug disposition Gene regulation
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844025000088
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