The prognostic value of circulating tumor DNA in malignant melanoma patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis

The prognostic value of circulating tumor DNA in malignant melanoma patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis

BackgroundCirculating tumor DNA (ctDNA) is an emerging biomarker in malignant melanoma(MM), and high levels of ctDNA may reflect a higher tumor load. However, its prognostic value for MM receiving immune checkpoint inhibitors(ICI) remains controversial. This meta-analysis aimed to elucidate the prog...

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Bibliographic Details
Main Authors: Lei Liu, Shufu Hou, Aiping Zhu, Bing Yan, Linchuan Li, Dandan Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
circulating tumor DNA
immune checkpoint inhibitors
malignant melanoma
overall survival
progression-free survival
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1520441/full
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