Adsorption of Paracetamol and Acetylsalicylic Acid onto Commercial Activated Carbons

The adsorption of paracetamol (PAR) and acetylsalicylic acid (ASA) onto high-surface-area, commercial activated carbons was investigated at 26°C via adsorption isotherms at different pH values, including pH 1.5 to simulate conditions existing in the stomach. A wide-ranging characterization of the ca...

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Main Authors: Sabina Beninati, Domenica Semeraro, Marina Mastragostino
Format: Article
Language:English
Published: SAGE Publishing 2008-11-01
Series:Adsorption Science & Technology
Online Access:https://doi.org/10.1260/026361708788251349
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author Sabina Beninati
Domenica Semeraro
Marina Mastragostino
author_facet Sabina Beninati
Domenica Semeraro
Marina Mastragostino
author_sort Sabina Beninati
collection DOAJ
description The adsorption of paracetamol (PAR) and acetylsalicylic acid (ASA) onto high-surface-area, commercial activated carbons was investigated at 26°C via adsorption isotherms at different pH values, including pH 1.5 to simulate conditions existing in the stomach. A wide-ranging characterization of the carbons, including analysis of their morphology and surface chemistry, was undertaken, with the actual surface areas of the carbons available for PAR and ASA adsorption being estimated by taking the molecular sizes of the drugs into account. This provided an understanding of the differences in the drug adsorption behaviour of the carbons.
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institution Kabale University
issn 0263-6174
2048-4038
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publishDate 2008-11-01
publisher SAGE Publishing
record_format Article
series Adsorption Science & Technology
spelling doaj-art-023dd8f39488491cb957deaceb259d932025-01-03T01:24:46ZengSAGE PublishingAdsorption Science & Technology0263-61742048-40382008-11-012610.1260/026361708788251349Adsorption of Paracetamol and Acetylsalicylic Acid onto Commercial Activated CarbonsSabina BeninatiDomenica SemeraroMarina MastragostinoThe adsorption of paracetamol (PAR) and acetylsalicylic acid (ASA) onto high-surface-area, commercial activated carbons was investigated at 26°C via adsorption isotherms at different pH values, including pH 1.5 to simulate conditions existing in the stomach. A wide-ranging characterization of the carbons, including analysis of their morphology and surface chemistry, was undertaken, with the actual surface areas of the carbons available for PAR and ASA adsorption being estimated by taking the molecular sizes of the drugs into account. This provided an understanding of the differences in the drug adsorption behaviour of the carbons.https://doi.org/10.1260/026361708788251349
spellingShingle Sabina Beninati
Domenica Semeraro
Marina Mastragostino
Adsorption of Paracetamol and Acetylsalicylic Acid onto Commercial Activated Carbons
Adsorption Science & Technology
title Adsorption of Paracetamol and Acetylsalicylic Acid onto Commercial Activated Carbons
title_full Adsorption of Paracetamol and Acetylsalicylic Acid onto Commercial Activated Carbons
title_fullStr Adsorption of Paracetamol and Acetylsalicylic Acid onto Commercial Activated Carbons
title_full_unstemmed Adsorption of Paracetamol and Acetylsalicylic Acid onto Commercial Activated Carbons
title_short Adsorption of Paracetamol and Acetylsalicylic Acid onto Commercial Activated Carbons
title_sort adsorption of paracetamol and acetylsalicylic acid onto commercial activated carbons
url https://doi.org/10.1260/026361708788251349
work_keys_str_mv AT sabinabeninati adsorptionofparacetamolandacetylsalicylicacidontocommercialactivatedcarbons
AT domenicasemeraro adsorptionofparacetamolandacetylsalicylicacidontocommercialactivatedcarbons
AT marinamastragostino adsorptionofparacetamolandacetylsalicylicacidontocommercialactivatedcarbons