Hairy B-cell lymphoproliferative disorder and its differential diagnosis: a case with long-term follow-up
Hairy B-cell lymphoproliferative disorder (HBLD) is one of chronic polyclonal B-cell lymphocytosis. We report a 47-year-old female Japanese patient diagnosed as having HBLD based on lymphocytosis with hairy cell appearance and characteristic phenotypes including CD11c+, and without B-cell monoclonal...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2017-09-01
|
| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
| Online Access: | http://www.mjhid.org/index.php/mjhid/article/view/3056 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846095905974910976 |
|---|---|
| author | Kensuke Matsuda Yosuke Matsumoto Mihiko Yoshida Kazuho Shimura Hiroto Kaneko Tohru Inaba Shigeo Horiike Junya Kuroda Masafumi Taniwaki |
| author_facet | Kensuke Matsuda Yosuke Matsumoto Mihiko Yoshida Kazuho Shimura Hiroto Kaneko Tohru Inaba Shigeo Horiike Junya Kuroda Masafumi Taniwaki |
| author_sort | Kensuke Matsuda |
| collection | DOAJ |
| description | Hairy B-cell lymphoproliferative disorder (HBLD) is one of chronic polyclonal B-cell lymphocytosis. We report a 47-year-old female Japanese patient diagnosed as having HBLD based on lymphocytosis with hairy cell appearance and characteristic phenotypes including CD11c+, and without B-cell monoclonalities. She was a non-smoker, and possessed HLA-DR4. She has been closely followed up without treatment and lymphoma development for over five years. Although this disease is quite rare and has been reported, to our knowledge, in only 13 Japanese cases, an accurate diagnosis, particularly differential diagnosis from persistent polyclonal B-cell lymphocytosis or hairy cell leukemia-Japanese variant is essential for the prevention of unnecessary treatments. |
| format | Article |
| id | doaj-art-0231e8b933714b3e86d0d24131334463 |
| institution | Kabale University |
| issn | 2035-3006 |
| language | English |
| publishDate | 2017-09-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-0231e8b933714b3e86d0d241313344632025-01-02T08:47:01ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062017-09-0191e2017054e201705410.4084/mjhid.2017.0541708Hairy B-cell lymphoproliferative disorder and its differential diagnosis: a case with long-term follow-upKensuke MatsudaYosuke MatsumotoMihiko YoshidaKazuho ShimuraHiroto KanekoTohru InabaShigeo HoriikeJunya KurodaMasafumi TaniwakiHairy B-cell lymphoproliferative disorder (HBLD) is one of chronic polyclonal B-cell lymphocytosis. We report a 47-year-old female Japanese patient diagnosed as having HBLD based on lymphocytosis with hairy cell appearance and characteristic phenotypes including CD11c+, and without B-cell monoclonalities. She was a non-smoker, and possessed HLA-DR4. She has been closely followed up without treatment and lymphoma development for over five years. Although this disease is quite rare and has been reported, to our knowledge, in only 13 Japanese cases, an accurate diagnosis, particularly differential diagnosis from persistent polyclonal B-cell lymphocytosis or hairy cell leukemia-Japanese variant is essential for the prevention of unnecessary treatments.http://www.mjhid.org/index.php/mjhid/article/view/3056 |
| spellingShingle | Kensuke Matsuda Yosuke Matsumoto Mihiko Yoshida Kazuho Shimura Hiroto Kaneko Tohru Inaba Shigeo Horiike Junya Kuroda Masafumi Taniwaki Hairy B-cell lymphoproliferative disorder and its differential diagnosis: a case with long-term follow-up Mediterranean Journal of Hematology and Infectious Diseases |
| title | Hairy B-cell lymphoproliferative disorder and its differential diagnosis: a case with long-term follow-up |
| title_full | Hairy B-cell lymphoproliferative disorder and its differential diagnosis: a case with long-term follow-up |
| title_fullStr | Hairy B-cell lymphoproliferative disorder and its differential diagnosis: a case with long-term follow-up |
| title_full_unstemmed | Hairy B-cell lymphoproliferative disorder and its differential diagnosis: a case with long-term follow-up |
| title_short | Hairy B-cell lymphoproliferative disorder and its differential diagnosis: a case with long-term follow-up |
| title_sort | hairy b cell lymphoproliferative disorder and its differential diagnosis a case with long term follow up |
| url | http://www.mjhid.org/index.php/mjhid/article/view/3056 |
| work_keys_str_mv | AT kensukematsuda hairybcelllymphoproliferativedisorderanditsdifferentialdiagnosisacasewithlongtermfollowup AT yosukematsumoto hairybcelllymphoproliferativedisorderanditsdifferentialdiagnosisacasewithlongtermfollowup AT mihikoyoshida hairybcelllymphoproliferativedisorderanditsdifferentialdiagnosisacasewithlongtermfollowup AT kazuhoshimura hairybcelllymphoproliferativedisorderanditsdifferentialdiagnosisacasewithlongtermfollowup AT hirotokaneko hairybcelllymphoproliferativedisorderanditsdifferentialdiagnosisacasewithlongtermfollowup AT tohruinaba hairybcelllymphoproliferativedisorderanditsdifferentialdiagnosisacasewithlongtermfollowup AT shigeohoriike hairybcelllymphoproliferativedisorderanditsdifferentialdiagnosisacasewithlongtermfollowup AT junyakuroda hairybcelllymphoproliferativedisorderanditsdifferentialdiagnosisacasewithlongtermfollowup AT masafumitaniwaki hairybcelllymphoproliferativedisorderanditsdifferentialdiagnosisacasewithlongtermfollowup |