IDOL N342S Variant, Atherosclerosis Progression and Cardiovascular Disorders in the Italian General Population.

IDOL N342S Variant, Atherosclerosis Progression and Cardiovascular Disorders in the Italian General Population.

Inducible degrader of the low density lipoprotein receptor (IDOL), is an E3 ubiquitin ligase that negatively modulates low density lipoprotein receptor (LDL-R) expression. Genome-wide association studies (GWAS) indicated that genetic variants in IDOL gene contributes to variation in LDL-C plasma lev...

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Bibliographic Details
Main Authors: Ashish Dhyani, Gianpaolo Tibolla, Andrea Baragetti, Katia Garlaschelli, Fabio Pellegatta, Liliana Grigore, Giuseppe Danilo Norata, Alberico Luigi Catapano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0122414
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