Percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysis
Abstract Background There is still controversy about the best minimally invasive surgical method for the treatment of calyceal diverticulum calculi. We conducted meta-analysis to evaluate the effectiveness and safety of PCNL and FURL in the treatment of calyceal diverticulum calculi. Methods We sear...
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2025-01-01
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Online Access: | https://doi.org/10.1186/s12894-024-01655-w |
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author | Conglei Hu Rui Ma Yongxiang Shao Zilong Liang Meng Cheng Haofeng Pang Liping Yao Fei Liu |
author_facet | Conglei Hu Rui Ma Yongxiang Shao Zilong Liang Meng Cheng Haofeng Pang Liping Yao Fei Liu |
author_sort | Conglei Hu |
collection | DOAJ |
description | Abstract Background There is still controversy about the best minimally invasive surgical method for the treatment of calyceal diverticulum calculi. We conducted meta-analysis to evaluate the effectiveness and safety of PCNL and FURL in the treatment of calyceal diverticulum calculi. Methods We searched Pubmed, Cochrane Library, Web of Science, Embase, Clinical trial platform, CNKI, VIP until April 2024. We utilized the Newcastle–Ottawa Scale (NOS, 0 to 9 stars) to assess the quality of the included literature. Results Totally 15 high-quality studies with 755 patients were included in the meta-analysis. Meta-analysis showed that FURL group was better than PCNL group in blood loss [SMD = 1.713, 95%CI:(0.858, 2.568), Z = 3.928, P = 0.000] and hospital stay [SMD = 2.611, 95%CI: (1.726, 3.496), Z = 5.784, P = 0.000], there was no significant difference in operating time [SMD = 0.079, 95%CI:(-0.43, 0.589), Z = 0.306, P = 0.760], complication rate [OR = 1.793,95%CI: (0.952,2.602), Z = 1.586, P = 0.113], stone-free rate [OR = 1.339, 95%CI: (0.576, 3.112), Z = 0.678, P = 0.497] and symptom-free rate [OR = 3.826,95%CI: (0.561,10.238), Z = 0.966, P = 0.334] as well. Conclusion Whether FURL is indeed superior to PCNL in safety, whether FURL's efficacy is really close to PCNL, and whether FURL can surpass PCNL as the first choice for the treatment of renal diverticulum stones in the future need to be further verified by multi-center, large-sample and high-quality studies. |
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institution | Kabale University |
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language | English |
publishDate | 2025-01-01 |
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spelling | doaj-art-02261df1102149f19094e08f3c48b5b22025-01-05T12:47:46ZengBMCBMC Urology1471-24902025-01-0125111210.1186/s12894-024-01655-wPercutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysisConglei Hu0Rui Ma1Yongxiang Shao2Zilong Liang3Meng Cheng4Haofeng Pang5Liping Yao6Fei Liu7Department of Urology, Xijing Hospital, Air Force Medical UniversityDepartment of Geriatrics, Xijing Hospital, Air Force Medical UniversityDepartment of Urology, Xijing Hospital, Air Force Medical UniversityDepartment of Urology, Xijing Hospital, Air Force Medical UniversityDepartment of Urology, Xijing Hospital, Air Force Medical UniversityDepartment of Urology, Xijing Hospital, Air Force Medical UniversityNational Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Air Force Medical UniversityDepartment of Urology, Xijing Hospital, Air Force Medical UniversityAbstract Background There is still controversy about the best minimally invasive surgical method for the treatment of calyceal diverticulum calculi. We conducted meta-analysis to evaluate the effectiveness and safety of PCNL and FURL in the treatment of calyceal diverticulum calculi. Methods We searched Pubmed, Cochrane Library, Web of Science, Embase, Clinical trial platform, CNKI, VIP until April 2024. We utilized the Newcastle–Ottawa Scale (NOS, 0 to 9 stars) to assess the quality of the included literature. Results Totally 15 high-quality studies with 755 patients were included in the meta-analysis. Meta-analysis showed that FURL group was better than PCNL group in blood loss [SMD = 1.713, 95%CI:(0.858, 2.568), Z = 3.928, P = 0.000] and hospital stay [SMD = 2.611, 95%CI: (1.726, 3.496), Z = 5.784, P = 0.000], there was no significant difference in operating time [SMD = 0.079, 95%CI:(-0.43, 0.589), Z = 0.306, P = 0.760], complication rate [OR = 1.793,95%CI: (0.952,2.602), Z = 1.586, P = 0.113], stone-free rate [OR = 1.339, 95%CI: (0.576, 3.112), Z = 0.678, P = 0.497] and symptom-free rate [OR = 3.826,95%CI: (0.561,10.238), Z = 0.966, P = 0.334] as well. Conclusion Whether FURL is indeed superior to PCNL in safety, whether FURL's efficacy is really close to PCNL, and whether FURL can surpass PCNL as the first choice for the treatment of renal diverticulum stones in the future need to be further verified by multi-center, large-sample and high-quality studies.https://doi.org/10.1186/s12894-024-01655-wCalyceal diverticulum calculiPercutaneous nephrolithotomyFlexible ureteroscopic lithotripsyRetrograde intrarenal surgeryMeta-analysis |
spellingShingle | Conglei Hu Rui Ma Yongxiang Shao Zilong Liang Meng Cheng Haofeng Pang Liping Yao Fei Liu Percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysis BMC Urology Calyceal diverticulum calculi Percutaneous nephrolithotomy Flexible ureteroscopic lithotripsy Retrograde intrarenal surgery Meta-analysis |
title | Percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysis |
title_full | Percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysis |
title_fullStr | Percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysis |
title_full_unstemmed | Percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysis |
title_short | Percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysis |
title_sort | percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi a meta analysis |
topic | Calyceal diverticulum calculi Percutaneous nephrolithotomy Flexible ureteroscopic lithotripsy Retrograde intrarenal surgery Meta-analysis |
url | https://doi.org/10.1186/s12894-024-01655-w |
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