Percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysis

Abstract Background There is still controversy about the best minimally invasive surgical method for the treatment of calyceal diverticulum calculi. We conducted meta-analysis to evaluate the effectiveness and safety of PCNL and FURL in the treatment of calyceal diverticulum calculi. Methods We sear...

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Main Authors: Conglei Hu, Rui Ma, Yongxiang Shao, Zilong Liang, Meng Cheng, Haofeng Pang, Liping Yao, Fei Liu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Urology
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Online Access:https://doi.org/10.1186/s12894-024-01655-w
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author Conglei Hu
Rui Ma
Yongxiang Shao
Zilong Liang
Meng Cheng
Haofeng Pang
Liping Yao
Fei Liu
author_facet Conglei Hu
Rui Ma
Yongxiang Shao
Zilong Liang
Meng Cheng
Haofeng Pang
Liping Yao
Fei Liu
author_sort Conglei Hu
collection DOAJ
description Abstract Background There is still controversy about the best minimally invasive surgical method for the treatment of calyceal diverticulum calculi. We conducted meta-analysis to evaluate the effectiveness and safety of PCNL and FURL in the treatment of calyceal diverticulum calculi. Methods We searched Pubmed, Cochrane Library, Web of Science, Embase, Clinical trial platform, CNKI, VIP until April 2024. We utilized the Newcastle–Ottawa Scale (NOS, 0 to 9 stars) to assess the quality of the included literature. Results Totally 15 high-quality studies with 755 patients were included in the meta-analysis. Meta-analysis showed that FURL group was better than PCNL group in blood loss [SMD = 1.713, 95%CI:(0.858, 2.568), Z = 3.928, P = 0.000] and hospital stay [SMD = 2.611, 95%CI: (1.726, 3.496), Z = 5.784, P = 0.000], there was no significant difference in operating time [SMD = 0.079, 95%CI:(-0.43, 0.589), Z = 0.306, P = 0.760], complication rate [OR = 1.793,95%CI: (0.952,2.602), Z = 1.586, P = 0.113], stone-free rate [OR = 1.339, 95%CI: (0.576, 3.112), Z = 0.678, P = 0.497] and symptom-free rate [OR = 3.826,95%CI: (0.561,10.238), Z = 0.966, P = 0.334] as well. Conclusion Whether FURL is indeed superior to PCNL in safety, whether FURL's efficacy is really close to PCNL, and whether FURL can surpass PCNL as the first choice for the treatment of renal diverticulum stones in the future need to be further verified by multi-center, large-sample and high-quality studies.
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spelling doaj-art-02261df1102149f19094e08f3c48b5b22025-01-05T12:47:46ZengBMCBMC Urology1471-24902025-01-0125111210.1186/s12894-024-01655-wPercutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysisConglei Hu0Rui Ma1Yongxiang Shao2Zilong Liang3Meng Cheng4Haofeng Pang5Liping Yao6Fei Liu7Department of Urology, Xijing Hospital, Air Force Medical UniversityDepartment of Geriatrics, Xijing Hospital, Air Force Medical UniversityDepartment of Urology, Xijing Hospital, Air Force Medical UniversityDepartment of Urology, Xijing Hospital, Air Force Medical UniversityDepartment of Urology, Xijing Hospital, Air Force Medical UniversityDepartment of Urology, Xijing Hospital, Air Force Medical UniversityNational Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Air Force Medical UniversityDepartment of Urology, Xijing Hospital, Air Force Medical UniversityAbstract Background There is still controversy about the best minimally invasive surgical method for the treatment of calyceal diverticulum calculi. We conducted meta-analysis to evaluate the effectiveness and safety of PCNL and FURL in the treatment of calyceal diverticulum calculi. Methods We searched Pubmed, Cochrane Library, Web of Science, Embase, Clinical trial platform, CNKI, VIP until April 2024. We utilized the Newcastle–Ottawa Scale (NOS, 0 to 9 stars) to assess the quality of the included literature. Results Totally 15 high-quality studies with 755 patients were included in the meta-analysis. Meta-analysis showed that FURL group was better than PCNL group in blood loss [SMD = 1.713, 95%CI:(0.858, 2.568), Z = 3.928, P = 0.000] and hospital stay [SMD = 2.611, 95%CI: (1.726, 3.496), Z = 5.784, P = 0.000], there was no significant difference in operating time [SMD = 0.079, 95%CI:(-0.43, 0.589), Z = 0.306, P = 0.760], complication rate [OR = 1.793,95%CI: (0.952,2.602), Z = 1.586, P = 0.113], stone-free rate [OR = 1.339, 95%CI: (0.576, 3.112), Z = 0.678, P = 0.497] and symptom-free rate [OR = 3.826,95%CI: (0.561,10.238), Z = 0.966, P = 0.334] as well. Conclusion Whether FURL is indeed superior to PCNL in safety, whether FURL's efficacy is really close to PCNL, and whether FURL can surpass PCNL as the first choice for the treatment of renal diverticulum stones in the future need to be further verified by multi-center, large-sample and high-quality studies.https://doi.org/10.1186/s12894-024-01655-wCalyceal diverticulum calculiPercutaneous nephrolithotomyFlexible ureteroscopic lithotripsyRetrograde intrarenal surgeryMeta-analysis
spellingShingle Conglei Hu
Rui Ma
Yongxiang Shao
Zilong Liang
Meng Cheng
Haofeng Pang
Liping Yao
Fei Liu
Percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysis
BMC Urology
Calyceal diverticulum calculi
Percutaneous nephrolithotomy
Flexible ureteroscopic lithotripsy
Retrograde intrarenal surgery
Meta-analysis
title Percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysis
title_full Percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysis
title_fullStr Percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysis
title_full_unstemmed Percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysis
title_short Percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysis
title_sort percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi a meta analysis
topic Calyceal diverticulum calculi
Percutaneous nephrolithotomy
Flexible ureteroscopic lithotripsy
Retrograde intrarenal surgery
Meta-analysis
url https://doi.org/10.1186/s12894-024-01655-w
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