Design and optimization of hollow microneedle spacing for three materials using finite element methods

Design and optimization of hollow microneedle spacing for three materials using finite element methods

Abstract The main advantages of microneedles are precise drug delivery through human skin, minimal tissue damage and painlessness. We conducted structural analysis and skin puncture studies of hollow microneedles using ANSYS for three materials: Hafnium Dioxide (HfO2), Polyglycolic acid (PGA) and Po...

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Bibliographic Details
Main Authors: Xiaodan Zhang, Qifei Gu, Xue Sui, Jie Zhang, Jingwei Liu, Rui Zhou
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Hollow microneedle
Finite element analysis
Skin model
Spacing design
Mechanical strength
Puncture force
Online Access:https://doi.org/10.1038/s41598-024-82564-8
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