Resilience Against Depression Disparities (RADD): a protocol for a randomised comparative effectiveness trial for depression among predominantly low-income, racial/ethnic, sexual and gender minorities

Introduction Depression is the leading cause of adult disability and common among sexual and gender minority (SGM) adults. The current study builds on findings showing the effectiveness of depression quality improvement (QI) and delivery of cognitive behavioural therapy (CBT) skills provided by comm...

Full description

Saved in:
Bibliographic Details
Main Authors: Jeanne Miranda, Sylvanna Maria Vargas, Ashley Wennerstrom, Nancy Alfaro, Thomas Belin, Krystal Griffith, Catherine Haywood, Felica Jones, Mitchell R Lunn, Diana Meyers, Juno Obedin-Maliver, Miranda Pollock, Cathy D Sherbourne, Benjamin F Springgate, Olivia K Sugarman, Emily Rey, Clarence Williams, Pluscedia Williams, Bowen Chung
Format: Article
Language:English
Published: BMJ Publishing Group 2019-10-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/9/10/e031099.full
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1846126178437431296
author Jeanne Miranda
Sylvanna Maria Vargas
Ashley Wennerstrom
Nancy Alfaro
Thomas Belin
Krystal Griffith
Catherine Haywood
Felica Jones
Mitchell R Lunn
Diana Meyers
Juno Obedin-Maliver
Miranda Pollock
Cathy D Sherbourne
Benjamin F Springgate
Olivia K Sugarman
Emily Rey
Clarence Williams
Pluscedia Williams
Bowen Chung
author_facet Jeanne Miranda
Sylvanna Maria Vargas
Ashley Wennerstrom
Nancy Alfaro
Thomas Belin
Krystal Griffith
Catherine Haywood
Felica Jones
Mitchell R Lunn
Diana Meyers
Juno Obedin-Maliver
Miranda Pollock
Cathy D Sherbourne
Benjamin F Springgate
Olivia K Sugarman
Emily Rey
Clarence Williams
Pluscedia Williams
Bowen Chung
author_sort Jeanne Miranda
collection DOAJ
description Introduction Depression is the leading cause of adult disability and common among sexual and gender minority (SGM) adults. The current study builds on findings showing the effectiveness of depression quality improvement (QI) and delivery of cognitive behavioural therapy (CBT) skills provided by community health workers in reducing depression. Depression QI approaches across healthcare and social/community services in safety-net settings have shown improvements in mental wellness, mental health quality of life and depression over 12 months. Further, a randomised study showed improved depression among low-income racial/ethnic minorities enrolled in a CBT-informed resiliency class (Building Resilience and Increasing Community Hope (B-RICH)). The current protocol describes a comparativeness effectiveness study to evaluate whether predominantly low-income, SGM racial/ethnic minority adults randomised to a CBT-informed resiliency class have improvements in depressive symptoms over and above community-engaged QI resources and training only.Methods and analysis The study approached three clusters of four to five programs serving predominantly SGM and racial/ethnic minority communities in the USA: two clusters in Los Angeles, California, and one in New Orleans, Louisiana. Clusters are comprised of one primary care, one mental health and two to three community agencies (eg, faith-based, social services/support, advocacy). All programs received depression QI training. The current study employed a community-partnered participatory research model to adapt the CBT-informed resiliency class, B-RICH+, to SGM communities. Study participants were screened and recruited in person from participating programs, and will complete baseline, 6- and 12-month survey follow-ups. Participants were depressed adults (8-item Patient Health Questionnaire ≥10; ≥18 years of age) who provided contact information. Enrolled participants were individually randomised to B-RICH+ or depression QI alone. Primary outcomes are depressive symptoms; secondary outcomes are mental health quality of life, mental wellness and physical health quality of life. Data collection for this study is ongoing.Ethics and dissemination The current study was approved by the UCLA Institutional Review Board. Study findings will be disseminated through scientific publications and community conferences.Trial registration number https://clinicaltrials.gov/ct2/show/NCT02986126
format Article
id doaj-art-01cfa7af957d43759ff9d7123d7cdb6e
institution Kabale University
issn 2044-6055
language English
publishDate 2019-10-01
publisher BMJ Publishing Group
record_format Article
series BMJ Open
spelling doaj-art-01cfa7af957d43759ff9d7123d7cdb6e2024-12-13T02:45:09ZengBMJ Publishing GroupBMJ Open2044-60552019-10-0191010.1136/bmjopen-2019-031099Resilience Against Depression Disparities (RADD): a protocol for a randomised comparative effectiveness trial for depression among predominantly low-income, racial/ethnic, sexual and gender minoritiesJeanne Miranda0Sylvanna Maria Vargas1Ashley Wennerstrom2Nancy Alfaro3Thomas Belin4Krystal Griffith5Catherine Haywood6Felica Jones7Mitchell R Lunn8Diana Meyers9Juno Obedin-Maliver10Miranda Pollock11Cathy D Sherbourne12Benjamin F Springgate13Olivia K Sugarman14Emily Rey15Clarence Williams16Pluscedia Williams17Bowen Chung18Center for Health Services and Society, University of California Los Angeles, Los Angeles, California, USA1 Psychology, University of Southern California, Los Angeles, California, USA4 School of Medicine, Tulane University, New Orleans, Louisiana, USA2 Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, California, USA2 Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, California, USA2 Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, California, USA7 Tulane Prevention Research Center, Tulane University, New Orleans, Louisiana, USA9 Healthy African American Families II, Los Angeles, California, USA10 Department of Medicine, Stanford University School of Medicine, Stanford, California, USA12 Saint Anna’s Episcopal Church, New Orleans, Louisiana, USA10 Department of Medicine, Stanford University School of Medicine, Stanford, California, USA14 Section of Community and Population Medicine, Department of Medicine, Louisiana State University School of Medicine, New Orleans, Louisiana, USA15 RAND Corporation, Los Angeles, California, USA14 Section of Community and Population Medicine, Department of Medicine, Louisiana State University School of Medicine, New Orleans, Louisiana, USA14 Section of Community and Population Medicine, Department of Medicine, Louisiana State University School of Medicine, New Orleans, Louisiana, USA18 LGBT Community Center, New Orleans, Louisiana, USA9 Healthy African American Families II, Los Angeles, California, USA9 Healthy African American Families II, Los Angeles, California, USA2 Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, California, USAIntroduction Depression is the leading cause of adult disability and common among sexual and gender minority (SGM) adults. The current study builds on findings showing the effectiveness of depression quality improvement (QI) and delivery of cognitive behavioural therapy (CBT) skills provided by community health workers in reducing depression. Depression QI approaches across healthcare and social/community services in safety-net settings have shown improvements in mental wellness, mental health quality of life and depression over 12 months. Further, a randomised study showed improved depression among low-income racial/ethnic minorities enrolled in a CBT-informed resiliency class (Building Resilience and Increasing Community Hope (B-RICH)). The current protocol describes a comparativeness effectiveness study to evaluate whether predominantly low-income, SGM racial/ethnic minority adults randomised to a CBT-informed resiliency class have improvements in depressive symptoms over and above community-engaged QI resources and training only.Methods and analysis The study approached three clusters of four to five programs serving predominantly SGM and racial/ethnic minority communities in the USA: two clusters in Los Angeles, California, and one in New Orleans, Louisiana. Clusters are comprised of one primary care, one mental health and two to three community agencies (eg, faith-based, social services/support, advocacy). All programs received depression QI training. The current study employed a community-partnered participatory research model to adapt the CBT-informed resiliency class, B-RICH+, to SGM communities. Study participants were screened and recruited in person from participating programs, and will complete baseline, 6- and 12-month survey follow-ups. Participants were depressed adults (8-item Patient Health Questionnaire ≥10; ≥18 years of age) who provided contact information. Enrolled participants were individually randomised to B-RICH+ or depression QI alone. Primary outcomes are depressive symptoms; secondary outcomes are mental health quality of life, mental wellness and physical health quality of life. Data collection for this study is ongoing.Ethics and dissemination The current study was approved by the UCLA Institutional Review Board. Study findings will be disseminated through scientific publications and community conferences.Trial registration number https://clinicaltrials.gov/ct2/show/NCT02986126https://bmjopen.bmj.com/content/9/10/e031099.full
spellingShingle Jeanne Miranda
Sylvanna Maria Vargas
Ashley Wennerstrom
Nancy Alfaro
Thomas Belin
Krystal Griffith
Catherine Haywood
Felica Jones
Mitchell R Lunn
Diana Meyers
Juno Obedin-Maliver
Miranda Pollock
Cathy D Sherbourne
Benjamin F Springgate
Olivia K Sugarman
Emily Rey
Clarence Williams
Pluscedia Williams
Bowen Chung
Resilience Against Depression Disparities (RADD): a protocol for a randomised comparative effectiveness trial for depression among predominantly low-income, racial/ethnic, sexual and gender minorities
BMJ Open
title Resilience Against Depression Disparities (RADD): a protocol for a randomised comparative effectiveness trial for depression among predominantly low-income, racial/ethnic, sexual and gender minorities
title_full Resilience Against Depression Disparities (RADD): a protocol for a randomised comparative effectiveness trial for depression among predominantly low-income, racial/ethnic, sexual and gender minorities
title_fullStr Resilience Against Depression Disparities (RADD): a protocol for a randomised comparative effectiveness trial for depression among predominantly low-income, racial/ethnic, sexual and gender minorities
title_full_unstemmed Resilience Against Depression Disparities (RADD): a protocol for a randomised comparative effectiveness trial for depression among predominantly low-income, racial/ethnic, sexual and gender minorities
title_short Resilience Against Depression Disparities (RADD): a protocol for a randomised comparative effectiveness trial for depression among predominantly low-income, racial/ethnic, sexual and gender minorities
title_sort resilience against depression disparities radd a protocol for a randomised comparative effectiveness trial for depression among predominantly low income racial ethnic sexual and gender minorities
url https://bmjopen.bmj.com/content/9/10/e031099.full
work_keys_str_mv AT jeannemiranda resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT sylvannamariavargas resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT ashleywennerstrom resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT nancyalfaro resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT thomasbelin resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT krystalgriffith resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT catherinehaywood resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT felicajones resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT mitchellrlunn resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT dianameyers resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT junoobedinmaliver resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT mirandapollock resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT cathydsherbourne resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT benjaminfspringgate resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT oliviaksugarman resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT emilyrey resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT clarencewilliams resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT pluscediawilliams resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities
AT bowenchung resilienceagainstdepressiondisparitiesraddaprotocolforarandomisedcomparativeeffectivenesstrialfordepressionamongpredominantlylowincomeracialethnicsexualandgenderminorities