纳米金-表阿霉素复合体的体外抗肿瘤作用
摘 要:【目的】 观察纳米金-表阿霉素复合体(epirubicin-nanogold compounds, EPI- AuNP)能否抑制人脐静脉内皮细胞(human umbilical vein endothelial cells, HUVECs)、人肝癌细胞(HepG2)的增殖。【方法】 采用化学合成法制备EPI-AuNP,通过紫外-可见吸收光谱、荧光淬灭实验、动态光散射及Zeta电位变化对其进行鉴定。体外实验分为AuNP处理组、EPI处理组、EPI- AuNP处理组和空白对照组。将HUVECs、HepG2细胞分别接种于96孔板,培养24h后各组分别加入AuNP溶液、EPI溶液、EPI-Au...
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Format: | Article |
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Language: | zho |
Published: |
Editorial Office of Journal of Sun Yat-sen University
2012-01-01
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Series: | Zhongshan Daxue xuebao. Yixue kexue ban |
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Online Access: | http://xuebaoyx.sysu.edu.cn/zh/article/43575710/ |
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