Effect of adding Scutellaria baicalensis Georgi to feed on the microbial diversity in cattle feces

IntroductionInflammation and oxidative stress can seriously endanger the health and growth of beef cattle. Scutellaria baicalensis Georgi (SB) has significant anti-inflammatory and antioxidative effects. However, studies on the application of SB stems and leaves as roughage in animal husbandry are l...

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Main Authors: Junli Zhang, Xue Bai, Fen Li, Rina Na, Yun Ma, Xiaojun Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1641802/full
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author Junli Zhang
Xue Bai
Fen Li
Rina Na
Yun Ma
Xiaojun Liang
author_facet Junli Zhang
Xue Bai
Fen Li
Rina Na
Yun Ma
Xiaojun Liang
author_sort Junli Zhang
collection DOAJ
description IntroductionInflammation and oxidative stress can seriously endanger the health and growth of beef cattle. Scutellaria baicalensis Georgi (SB) has significant anti-inflammatory and antioxidative effects. However, studies on the application of SB stems and leaves as roughage in animal husbandry are limited. Therefore, in this study, we investigated the effects of adding different proportions of SB stems and leaves to roughage on the microbial diversity of bovine feces.MethodsIn total, 20 cattles (Simmental xlocal yellow cattle) were randomly divided into four groups: CON, G1, G2, and G3 (with 3%, 6%, and 9% SB stems and leaves added to the roughage, respectively). All cattles were exposed to pre-experimental conditions for 15 days and experimental conditions for 90 days. Growth performance indicators were measured on the 0th, 15th, 45th, and 90th days of the formal experiment. Blood was collected for measuring biochemical performance indices. Fresh fecal samples were collected on the 90th day for 16S sequencing to study the microbial diversity of cow feces.ResultsThe results showed that during the experiment, the F/G of the G1, G2, and G3 groups was significantly lower than that of the CON group (P < 0.05). The IL-10 content in the serum of the G3 group was significantly greater than that in the CON group (P < 0.05). The 16S rRNA results revealed significant differences in the composition of the bacterial community between the SB groups and the CON group. At the phylum level, adding the stems and leaves of SB significantly decreased the Firmicutes/Bacteroidetes ratio, and the relative abundances of Spirochaetes, Verrucomicrobia, and Proteobacteria decreased. At the genus level, Anaerovibrio, Epulopiscium, Akkermansia, Bacteroides, YRC22, Paludibacter, 5-7N15, Butyrivibrio, Prevotella, and Anaeroplasma were identified as markers of intergroup differences. These intergroup differential microbiota were associated with pathways such as amino acid biosynthesis, fatty acid and lipid biosynthesis, carbohydrate biosynthesis, carbohydrate degradation, nucleoside and nucleotide degradation, fermentation, glycolysis, the TCA cycle, glycan biosynthesis, and glycan degradation.DiscussionOur findings revealed that adding the stems and leaves of SB to feed can promote body growth and antioxidant capacity and increase the diversity of the gut microbiota. This new feeding strategy can improve the efficiency of cattle farming.
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spelling doaj-art-01c794e5728644c69d5f6ac9932e7f292025-08-22T09:52:31ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2025-08-011610.3389/fmicb.2025.16418021641802Effect of adding Scutellaria baicalensis Georgi to feed on the microbial diversity in cattle fecesJunli Zhang0Xue Bai1Fen Li2Rina Na3Yun Ma4Xiaojun Liang5Institute of Animal Science, Ningxia Academy of Agriculture and Forestry, Yinchuan, Ningxia, ChinaKey Laboratory of Ruminant Molecular and Cellular Breeding, College of Animal Science and Technology, Ningxia University, Yinchuan, ChinaSchool of Food Science and Engineering, Ningxia University, Yinchuan, Ningxia, ChinaKey Laboratory of Ruminant Molecular and Cellular Breeding, College of Animal Science and Technology, Ningxia University, Yinchuan, ChinaKey Laboratory of Ruminant Molecular and Cellular Breeding, College of Animal Science and Technology, Ningxia University, Yinchuan, ChinaInstitute of Animal Science, Ningxia Academy of Agriculture and Forestry, Yinchuan, Ningxia, ChinaIntroductionInflammation and oxidative stress can seriously endanger the health and growth of beef cattle. Scutellaria baicalensis Georgi (SB) has significant anti-inflammatory and antioxidative effects. However, studies on the application of SB stems and leaves as roughage in animal husbandry are limited. Therefore, in this study, we investigated the effects of adding different proportions of SB stems and leaves to roughage on the microbial diversity of bovine feces.MethodsIn total, 20 cattles (Simmental xlocal yellow cattle) were randomly divided into four groups: CON, G1, G2, and G3 (with 3%, 6%, and 9% SB stems and leaves added to the roughage, respectively). All cattles were exposed to pre-experimental conditions for 15 days and experimental conditions for 90 days. Growth performance indicators were measured on the 0th, 15th, 45th, and 90th days of the formal experiment. Blood was collected for measuring biochemical performance indices. Fresh fecal samples were collected on the 90th day for 16S sequencing to study the microbial diversity of cow feces.ResultsThe results showed that during the experiment, the F/G of the G1, G2, and G3 groups was significantly lower than that of the CON group (P < 0.05). The IL-10 content in the serum of the G3 group was significantly greater than that in the CON group (P < 0.05). The 16S rRNA results revealed significant differences in the composition of the bacterial community between the SB groups and the CON group. At the phylum level, adding the stems and leaves of SB significantly decreased the Firmicutes/Bacteroidetes ratio, and the relative abundances of Spirochaetes, Verrucomicrobia, and Proteobacteria decreased. At the genus level, Anaerovibrio, Epulopiscium, Akkermansia, Bacteroides, YRC22, Paludibacter, 5-7N15, Butyrivibrio, Prevotella, and Anaeroplasma were identified as markers of intergroup differences. These intergroup differential microbiota were associated with pathways such as amino acid biosynthesis, fatty acid and lipid biosynthesis, carbohydrate biosynthesis, carbohydrate degradation, nucleoside and nucleotide degradation, fermentation, glycolysis, the TCA cycle, glycan biosynthesis, and glycan degradation.DiscussionOur findings revealed that adding the stems and leaves of SB to feed can promote body growth and antioxidant capacity and increase the diversity of the gut microbiota. This new feeding strategy can improve the efficiency of cattle farming.https://www.frontiersin.org/articles/10.3389/fmicb.2025.1641802/fullbeef cattleScutellaria baicalensis Georgiproduction performancebiochemical indicatorsfecal microbes
spellingShingle Junli Zhang
Xue Bai
Fen Li
Rina Na
Yun Ma
Xiaojun Liang
Effect of adding Scutellaria baicalensis Georgi to feed on the microbial diversity in cattle feces
Frontiers in Microbiology
beef cattle
Scutellaria baicalensis Georgi
production performance
biochemical indicators
fecal microbes
title Effect of adding Scutellaria baicalensis Georgi to feed on the microbial diversity in cattle feces
title_full Effect of adding Scutellaria baicalensis Georgi to feed on the microbial diversity in cattle feces
title_fullStr Effect of adding Scutellaria baicalensis Georgi to feed on the microbial diversity in cattle feces
title_full_unstemmed Effect of adding Scutellaria baicalensis Georgi to feed on the microbial diversity in cattle feces
title_short Effect of adding Scutellaria baicalensis Georgi to feed on the microbial diversity in cattle feces
title_sort effect of adding scutellaria baicalensis georgi to feed on the microbial diversity in cattle feces
topic beef cattle
Scutellaria baicalensis Georgi
production performance
biochemical indicators
fecal microbes
url https://www.frontiersin.org/articles/10.3389/fmicb.2025.1641802/full
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