Design and Implementation of a Software System for Full-Process Animal Experiment Ethical Review
Institutions of higher education undertake a significant number of animal experiment projects with diverse types. To standardize animal experiments and ensure animal welfare, ethical review has become a core task for the Institutional Animal Care and Use Committee (IACUC) in these higher education i...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Laboratory Animal and Comparative Medicine
2024-12-01
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| Series: | Shiyan dongwu yu bijiao yixue |
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| Online Access: | https://www.slarc.org.cn/dwyx/CN/10.12300/j.issn.1674-5817.2024.086 |
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| author | XU Xiao WU Jiemin LIANG Yi YE Mingxia ZHOU Shunchang |
| author_facet | XU Xiao WU Jiemin LIANG Yi YE Mingxia ZHOU Shunchang |
| author_sort | XU Xiao |
| collection | DOAJ |
| description | Institutions of higher education undertake a significant number of animal experiment projects with diverse types. To standardize animal experiments and ensure animal welfare, ethical review has become a core task for the Institutional Animal Care and Use Committee (IACUC) in these higher education institutions. A key issue worth exploring is how to improve the efficiency of animal ethical reviews while maintaining systematic quality of supervision. Based on the current status of ethical reviews at the Laboratory Animal Center of Huazhong University of Science and Technology, this paper designs and implements a full-process ethical review software system. This system seeks to offer solutions for the ethical review and supervision of animal welfare in institutions of higher education through information technology. The system employs a full-process supervision philosophy of "pre-approval, in-process supervision, post-review," focusing on strengthening the review and approval of animal research protocols, as well as post-approval monitoring. At the pre-approval stage, the system optimizes the process for designated members involved in the project review, ensuring that all projects comply with ethical standards and legal regulations. At the in-process stage, veterinary verification and consultation are carried out by executive veterinarians, using a method of "offline inspections and online records" for supervision. At the post-review stage, researchers are required to provide retrospective data to evaluate the experimental process. Additionally, this paper provides an in-depth exploration of the software, detailing its functional and non-functional requirements, as well as its security considerations. It also delves into the comprehensive software architecture, process design, and operational details. Furthermore, it illustrates the system's operational efficacy and impact since its launch. This paper discusses the software's applicability and practicality, analyzing existing limitations and challenges, such as the difficulty of balancing experiment urgency with the stringent nature of review processes, and the traceability blind spots in post-approval supervision. Future research will continue to enhance the accuracy and strength of animal welfare ethical reviews and supervision through new technologies and methods. |
| format | Article |
| id | doaj-art-01ac15e6b0414061ac455a158ab8e27c |
| institution | Kabale University |
| issn | 1674-5817 |
| language | zho |
| publishDate | 2024-12-01 |
| publisher | Editorial Office of Laboratory Animal and Comparative Medicine |
| record_format | Article |
| series | Shiyan dongwu yu bijiao yixue |
| spelling | doaj-art-01ac15e6b0414061ac455a158ab8e27c2025-01-06T05:12:09ZzhoEditorial Office of Laboratory Animal and Comparative MedicineShiyan dongwu yu bijiao yixue1674-58172024-12-0144668269010.12300/j.issn.1674-5817.2024.0861674-5817（2024）06-0682-09Design and Implementation of a Software System for Full-Process Animal Experiment Ethical ReviewXU Xiao0WU Jiemin1LIANG Yi2YE Mingxia3ZHOU Shunchang4Laboratory Animal Center, Huazhong University of Science and Technology, Wuhan430030, ChinaLaboratory Animal Center, Huazhong University of Science and Technology, Wuhan430030, ChinaXiamen Baoyi Intelligent Technology Co., Ltd., Xiamen361000, ChinaLaboratory Animal Center, Huazhong University of Science and Technology, Wuhan430030, ChinaLaboratory Animal Center, Huazhong University of Science and Technology, Wuhan430030, ChinaInstitutions of higher education undertake a significant number of animal experiment projects with diverse types. To standardize animal experiments and ensure animal welfare, ethical review has become a core task for the Institutional Animal Care and Use Committee (IACUC) in these higher education institutions. A key issue worth exploring is how to improve the efficiency of animal ethical reviews while maintaining systematic quality of supervision. Based on the current status of ethical reviews at the Laboratory Animal Center of Huazhong University of Science and Technology, this paper designs and implements a full-process ethical review software system. This system seeks to offer solutions for the ethical review and supervision of animal welfare in institutions of higher education through information technology. The system employs a full-process supervision philosophy of "pre-approval, in-process supervision, post-review," focusing on strengthening the review and approval of animal research protocols, as well as post-approval monitoring. At the pre-approval stage, the system optimizes the process for designated members involved in the project review, ensuring that all projects comply with ethical standards and legal regulations. At the in-process stage, veterinary verification and consultation are carried out by executive veterinarians, using a method of "offline inspections and online records" for supervision. At the post-review stage, researchers are required to provide retrospective data to evaluate the experimental process. Additionally, this paper provides an in-depth exploration of the software, detailing its functional and non-functional requirements, as well as its security considerations. It also delves into the comprehensive software architecture, process design, and operational details. Furthermore, it illustrates the system's operational efficacy and impact since its launch. This paper discusses the software's applicability and practicality, analyzing existing limitations and challenges, such as the difficulty of balancing experiment urgency with the stringent nature of review processes, and the traceability blind spots in post-approval supervision. Future research will continue to enhance the accuracy and strength of animal welfare ethical reviews and supervision through new technologies and methods.https://www.slarc.org.cn/dwyx/CN/10.12300/j.issn.1674-5817.2024.086animal ethics and welfareethical reviewinformatizationsoftware designfull-process monitoring |
| spellingShingle | XU Xiao WU Jiemin LIANG Yi YE Mingxia ZHOU Shunchang Design and Implementation of a Software System for Full-Process Animal Experiment Ethical Review Shiyan dongwu yu bijiao yixue animal ethics and welfare ethical review informatization software design full-process monitoring |
| title | Design and Implementation of a Software System for Full-Process Animal Experiment Ethical Review |
| title_full | Design and Implementation of a Software System for Full-Process Animal Experiment Ethical Review |
| title_fullStr | Design and Implementation of a Software System for Full-Process Animal Experiment Ethical Review |
| title_full_unstemmed | Design and Implementation of a Software System for Full-Process Animal Experiment Ethical Review |
| title_short | Design and Implementation of a Software System for Full-Process Animal Experiment Ethical Review |
| title_sort | design and implementation of a software system for full process animal experiment ethical review |
| topic | animal ethics and welfare ethical review informatization software design full-process monitoring |
| url | https://www.slarc.org.cn/dwyx/CN/10.12300/j.issn.1674-5817.2024.086 |
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