The effect of antenatal steroids on fetal lung maturation between 34 and 36 weeks of pregnancy
Background and aim Preterm birth can happen as a consequence of unprompted preterm labor, involving the preterm premature ruptures of membranes, or medical treatments, like labor inductions or elective cesarean, which are initiated to decrease meager outcome accompanied with definite motherly or fet...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-04-01
|
| Series: | Al-Azhar Assiut Medical Journal |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/azmj.azmj_43_21 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841525268398735360 |
|---|---|
| author | Eman Y. Ahmad Abd El-Aziz G. El-Deen Al-Darwish Mahmoud M. Fouad |
| author_facet | Eman Y. Ahmad Abd El-Aziz G. El-Deen Al-Darwish Mahmoud M. Fouad |
| author_sort | Eman Y. Ahmad |
| collection | DOAJ |
| description | Background and aim
Preterm birth can happen as a consequence of unprompted preterm labor, involving the preterm premature ruptures of membranes, or medical treatments, like labor inductions or elective cesarean, which are initiated to decrease meager outcome accompanied with definite motherly or fetal condition.
The evaluation of the maturity of fetal lungs is suitable for defining the timing of birth in complicated pregnancy cases such as a history of blood loss, placenta previa, a history of a preceding classical cesarean birth, and a history of preceding uterine operation.
This work aimed to evaluate the effect of antenatal corticosteroid administration from the 34th week till the 37th week of gestation on neonatal outcome in cases at elevated risk of preterm labor.
Patients and methods
A case–control investigation was carried out in Al-Azhar University Hospitals in Assiut and Qena General Hospital including 500 pregnant women in their 34th to 36th week of gestation at elevated risks of preterm labor. The cases were allocated into two similar groups. The period of the work ranged from 6 to 12 months.
Results
There is a significant difference between the study groups regarding APGAR scoring at delivery and at 5 min, lamellar body count, and neonatal intensive care unit admission. There is no significant difference regarding weight of baby and time of termination. There is a significant difference between the studied groups regarding preterm labor and sex of the baby. There was a highly significant difference between the studied groups regarding neonatal intensive care unit admission. However, there was a significant difference between the studied groups regarding preterm labor.
Conclusion
Steroids have a significant benefit on fetal well-being even if used after 34 weeks of pregnancy. Steroids were given prophylactically to those who are recognized to have elevated risk of preterm labor. |
| format | Article |
| id | doaj-art-01a7c9dc9e934fcf8b93a77a774e86df |
| institution | Kabale University |
| issn | 1687-1693 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Al-Azhar Assiut Medical Journal |
| spelling | doaj-art-01a7c9dc9e934fcf8b93a77a774e86df2025-01-17T15:56:53ZengWolters Kluwer Medknow PublicationsAl-Azhar Assiut Medical Journal1687-16932024-04-01222707710.4103/azmj.azmj_43_21The effect of antenatal steroids on fetal lung maturation between 34 and 36 weeks of pregnancyEman Y. AhmadAbd El-Aziz G. El-Deen Al-DarwishMahmoud M. FouadBackground and aim Preterm birth can happen as a consequence of unprompted preterm labor, involving the preterm premature ruptures of membranes, or medical treatments, like labor inductions or elective cesarean, which are initiated to decrease meager outcome accompanied with definite motherly or fetal condition. The evaluation of the maturity of fetal lungs is suitable for defining the timing of birth in complicated pregnancy cases such as a history of blood loss, placenta previa, a history of a preceding classical cesarean birth, and a history of preceding uterine operation. This work aimed to evaluate the effect of antenatal corticosteroid administration from the 34th week till the 37th week of gestation on neonatal outcome in cases at elevated risk of preterm labor. Patients and methods A case–control investigation was carried out in Al-Azhar University Hospitals in Assiut and Qena General Hospital including 500 pregnant women in their 34th to 36th week of gestation at elevated risks of preterm labor. The cases were allocated into two similar groups. The period of the work ranged from 6 to 12 months. Results There is a significant difference between the study groups regarding APGAR scoring at delivery and at 5 min, lamellar body count, and neonatal intensive care unit admission. There is no significant difference regarding weight of baby and time of termination. There is a significant difference between the studied groups regarding preterm labor and sex of the baby. There was a highly significant difference between the studied groups regarding neonatal intensive care unit admission. However, there was a significant difference between the studied groups regarding preterm labor. Conclusion Steroids have a significant benefit on fetal well-being even if used after 34 weeks of pregnancy. Steroids were given prophylactically to those who are recognized to have elevated risk of preterm labor.https://journals.lww.com/10.4103/azmj.azmj_43_21antenatal steroidslung maturationlate pregnancylate preterm |
| spellingShingle | Eman Y. Ahmad Abd El-Aziz G. El-Deen Al-Darwish Mahmoud M. Fouad The effect of antenatal steroids on fetal lung maturation between 34 and 36 weeks of pregnancy Al-Azhar Assiut Medical Journal antenatal steroids lung maturation late pregnancy late preterm |
| title | The effect of antenatal steroids on fetal lung maturation between 34 and 36 weeks of pregnancy |
| title_full | The effect of antenatal steroids on fetal lung maturation between 34 and 36 weeks of pregnancy |
| title_fullStr | The effect of antenatal steroids on fetal lung maturation between 34 and 36 weeks of pregnancy |
| title_full_unstemmed | The effect of antenatal steroids on fetal lung maturation between 34 and 36 weeks of pregnancy |
| title_short | The effect of antenatal steroids on fetal lung maturation between 34 and 36 weeks of pregnancy |
| title_sort | effect of antenatal steroids on fetal lung maturation between 34 and 36 weeks of pregnancy |
| topic | antenatal steroids lung maturation late pregnancy late preterm |
| url | https://journals.lww.com/10.4103/azmj.azmj_43_21 |
| work_keys_str_mv | AT emanyahmad theeffectofantenatalsteroidsonfetallungmaturationbetween34and36weeksofpregnancy AT abdelazizgeldeenaldarwish theeffectofantenatalsteroidsonfetallungmaturationbetween34and36weeksofpregnancy AT mahmoudmfouad theeffectofantenatalsteroidsonfetallungmaturationbetween34and36weeksofpregnancy AT emanyahmad effectofantenatalsteroidsonfetallungmaturationbetween34and36weeksofpregnancy AT abdelazizgeldeenaldarwish effectofantenatalsteroidsonfetallungmaturationbetween34and36weeksofpregnancy AT mahmoudmfouad effectofantenatalsteroidsonfetallungmaturationbetween34and36weeksofpregnancy |