Identification of the Novel Tumor Suppressor Role of FOCAD/miR-491-5p to Inhibit Cancer Stemness, Drug Resistance and Metastasis via Regulating RABIF/MMP Signaling in Triple Negative Breast Cancer

Identification of the Novel Tumor Suppressor Role of FOCAD/miR-491-5p to Inhibit Cancer Stemness, Drug Resistance and Metastasis via Regulating RABIF/MMP Signaling in Triple Negative Breast Cancer

Triple negative breast cancer (TNBC) possesses poor prognosis mainly due to development of chemoresistance and lack of effective endocrine or targeted therapies. MiR-491-5p has been found to play a tumor suppressor role in many cancers including breast cancer. However, the precise role of miR-491-5p...

Full description

Saved in:
Bibliographic Details
Main Authors: Wei-Chieh Huang, Hsiang-Cheng Chi, Shiao-Lin Tung, Po-Ming Chen, Ya-Chi Shih, Yi-Ching Huang, Pei-Yi Chu
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
TNBC
miR-491-5p
FOCAD
RABIF
MMP
Online Access:https://www.mdpi.com/2073-4409/10/10/2524
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items