Case report: Innovative approach to esophageal cancer with right aortic arch: neoadjuvant immunotherapy and 3D reconstruction
BackgroundWe report a rare case of locally advanced esophageal cancer with a right aortic arch (RAA), successfully treated with neoadjuvant immunotherapy and minimally invasive esophagectomy, guided by three-dimensional (3D) reconstruction.Case presentationA 50-year-old male with stage III esophagea...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2024.1496265/full |
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| author | Chengwen Luo Zhilin Luo |
| author_facet | Chengwen Luo Zhilin Luo |
| author_sort | Chengwen Luo |
| collection | DOAJ |
| description | BackgroundWe report a rare case of locally advanced esophageal cancer with a right aortic arch (RAA), successfully treated with neoadjuvant immunotherapy and minimally invasive esophagectomy, guided by three-dimensional (3D) reconstruction.Case presentationA 50-year-old male with stage III esophageal squamous cell carcinoma (cT3N0M0) and RAA underwent four cycles of neoadjuvant immunotherapy with sintilimab, resulting in significant tumor regression. Minimally invasive esophagectomy was performed with the aid of preoperative 3D reconstruction, which was critical in navigating the complex vascular anatomy and ensuring surgical precision.ConclusionThis case demonstrates the efficacy of neoadjuvant immunotherapy combined with 3D reconstruction in managing esophageal cancer complicated by vascular anomalies. This approach offers a promising alternative for complex cases where conventional treatments pose higher risks. |
| format | Article |
| id | doaj-art-016153dfe45a42c096ecbefadb1ca581 |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-016153dfe45a42c096ecbefadb1ca5812025-01-13T05:10:16ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011410.3389/fonc.2024.14962651496265Case report: Innovative approach to esophageal cancer with right aortic arch: neoadjuvant immunotherapy and 3D reconstructionChengwen LuoZhilin LuoBackgroundWe report a rare case of locally advanced esophageal cancer with a right aortic arch (RAA), successfully treated with neoadjuvant immunotherapy and minimally invasive esophagectomy, guided by three-dimensional (3D) reconstruction.Case presentationA 50-year-old male with stage III esophageal squamous cell carcinoma (cT3N0M0) and RAA underwent four cycles of neoadjuvant immunotherapy with sintilimab, resulting in significant tumor regression. Minimally invasive esophagectomy was performed with the aid of preoperative 3D reconstruction, which was critical in navigating the complex vascular anatomy and ensuring surgical precision.ConclusionThis case demonstrates the efficacy of neoadjuvant immunotherapy combined with 3D reconstruction in managing esophageal cancer complicated by vascular anomalies. This approach offers a promising alternative for complex cases where conventional treatments pose higher risks.https://www.frontiersin.org/articles/10.3389/fonc.2024.1496265/fullesophageal cancerright aortic archimmunotherapythree-dimensional reconstructionminimally invasive surgery |
| spellingShingle | Chengwen Luo Zhilin Luo Case report: Innovative approach to esophageal cancer with right aortic arch: neoadjuvant immunotherapy and 3D reconstruction Frontiers in Oncology esophageal cancer right aortic arch immunotherapy three-dimensional reconstruction minimally invasive surgery |
| title | Case report: Innovative approach to esophageal cancer with right aortic arch: neoadjuvant immunotherapy and 3D reconstruction |
| title_full | Case report: Innovative approach to esophageal cancer with right aortic arch: neoadjuvant immunotherapy and 3D reconstruction |
| title_fullStr | Case report: Innovative approach to esophageal cancer with right aortic arch: neoadjuvant immunotherapy and 3D reconstruction |
| title_full_unstemmed | Case report: Innovative approach to esophageal cancer with right aortic arch: neoadjuvant immunotherapy and 3D reconstruction |
| title_short | Case report: Innovative approach to esophageal cancer with right aortic arch: neoadjuvant immunotherapy and 3D reconstruction |
| title_sort | case report innovative approach to esophageal cancer with right aortic arch neoadjuvant immunotherapy and 3d reconstruction |
| topic | esophageal cancer right aortic arch immunotherapy three-dimensional reconstruction minimally invasive surgery |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2024.1496265/full |
| work_keys_str_mv | AT chengwenluo casereportinnovativeapproachtoesophagealcancerwithrightaorticarchneoadjuvantimmunotherapyand3dreconstruction AT zhilinluo casereportinnovativeapproachtoesophagealcancerwithrightaorticarchneoadjuvantimmunotherapyand3dreconstruction |