Construction of a Vero cell line expression human KREMEN1 for the development of CVA6 vaccines

Construction of a Vero cell line expression human KREMEN1 for the development of CVA6 vaccines

Abstract Coxsackievirus A6 (CVA6) has emerged as a major pathogen causing hand, foot and mouth disease (HFMD) outbreaks worldwide. The CVA6 epidemic poses a new challenge in HFMD control since there is currently no vaccine available against CVA6 infections. The Vero cell line has been widely used in...

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Main Authors: Dongqing Zhang, Yuxiang Zou, Jiaying Wu, Longfa Xu, Zhifeng Ke, Yuanyuan Wu, Zhenhong Zhou, Mujin Fang, Ling Chen, Henggang Xu, Jianping Chu, Ningshao Xia, Rui Zhu, Tong Cheng
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Virology Journal
Subjects:
Coxsackievirus A6
Vero cell line
Human KREMEN1 receptor
Vaccine
Online Access:https://doi.org/10.1186/s12985-024-02618-1
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