COVID 19 and Immune Phenomenon in Children
The novel coronavirus, named as severe acute respiratory syndrome (SARS)-CoV-2 has emerged as a global emergency. In December 2019, from a local outbreak in Wuhan, China, it has rapidly progressed to a global pandemic causing high morbidity and mortality exhausting all health-care facilities. COVID-...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-04-01
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| Series: | Indian Journal of Medical Specialities |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/INJMS.INJMS_59_20 |
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| author | Anu Maheshwari Kaveri Pandit Virendra Kumar Deonath Mahto |
| author_facet | Anu Maheshwari Kaveri Pandit Virendra Kumar Deonath Mahto |
| author_sort | Anu Maheshwari |
| collection | DOAJ |
| description | The novel coronavirus, named as severe acute respiratory syndrome (SARS)-CoV-2 has emerged as a global emergency. In December 2019, from a local outbreak in Wuhan, China, it has rapidly progressed to a global pandemic causing high morbidity and mortality exhausting all health-care facilities. COVID-19 is like any other respiratory virus but has more propensity to infect the lower parts of the respiratory system, namely bronchioles and alveoli. The innate and adaptive immune response helps the body to fight the virus. Atypical presentations such as Kawasaki disease, chilblain like lesions and other cutaneous manifestations, systemic inflammatory response syndrome-like illness (Toxic shock syndrome), Guillain–Barre syndrome, and other immune-related disorders have also been reported in various countries. Rapidly increasing cases worldwide have aroused global concerns regarding the need to understand the immunopathogenesis of the virus and possible explanations for various atypical manifestations occurring in children. This review is aimed at providing a complete understanding of the probable immune response in children and might predict future therapeutic target points. |
| format | Article |
| id | doaj-art-00fef3d9019e4c7d8a62ec2e55fba584 |
| institution | Kabale University |
| issn | 0976-2884 0976-2892 |
| language | English |
| publishDate | 2020-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Medical Specialities |
| spelling | doaj-art-00fef3d9019e4c7d8a62ec2e55fba5842025-08-25T08:33:16ZengWolters Kluwer Medknow PublicationsIndian Journal of Medical Specialities0976-28840976-28922020-04-01112656910.4103/INJMS.INJMS_59_20COVID 19 and Immune Phenomenon in ChildrenAnu MaheshwariKaveri PanditVirendra KumarDeonath MahtoThe novel coronavirus, named as severe acute respiratory syndrome (SARS)-CoV-2 has emerged as a global emergency. In December 2019, from a local outbreak in Wuhan, China, it has rapidly progressed to a global pandemic causing high morbidity and mortality exhausting all health-care facilities. COVID-19 is like any other respiratory virus but has more propensity to infect the lower parts of the respiratory system, namely bronchioles and alveoli. The innate and adaptive immune response helps the body to fight the virus. Atypical presentations such as Kawasaki disease, chilblain like lesions and other cutaneous manifestations, systemic inflammatory response syndrome-like illness (Toxic shock syndrome), Guillain–Barre syndrome, and other immune-related disorders have also been reported in various countries. Rapidly increasing cases worldwide have aroused global concerns regarding the need to understand the immunopathogenesis of the virus and possible explanations for various atypical manifestations occurring in children. This review is aimed at providing a complete understanding of the probable immune response in children and might predict future therapeutic target points.https://journals.lww.com/10.4103/INJMS.INJMS_59_20covid-19kawasaki diseasemyocarditispediatric multi-system inflammatory syndrome |
| spellingShingle | Anu Maheshwari Kaveri Pandit Virendra Kumar Deonath Mahto COVID 19 and Immune Phenomenon in Children Indian Journal of Medical Specialities covid-19 kawasaki disease myocarditis pediatric multi-system inflammatory syndrome |
| title | COVID 19 and Immune Phenomenon in Children |
| title_full | COVID 19 and Immune Phenomenon in Children |
| title_fullStr | COVID 19 and Immune Phenomenon in Children |
| title_full_unstemmed | COVID 19 and Immune Phenomenon in Children |
| title_short | COVID 19 and Immune Phenomenon in Children |
| title_sort | covid 19 and immune phenomenon in children |
| topic | covid-19 kawasaki disease myocarditis pediatric multi-system inflammatory syndrome |
| url | https://journals.lww.com/10.4103/INJMS.INJMS_59_20 |
| work_keys_str_mv | AT anumaheshwari covid19andimmunephenomenoninchildren AT kaveripandit covid19andimmunephenomenoninchildren AT virendrakumar covid19andimmunephenomenoninchildren AT deonathmahto covid19andimmunephenomenoninchildren |